tetano
Editor, Senior Moderator
SAGE Open Med Case Rep
. 2024 Jul 26:12:2050313X241266436.
doi: 10.1177/2050313X241266436. eCollection 2024. A child with sickle cell disease admitted with coronavirus disease 2019 pneumonia and acute chest syndrome in pediatric intensive care unit: A case report
Mohammad Raza[SUP] 1 [/SUP], Saleh Saad Alshehri[SUP] 2 [/SUP], Mohsina Reshma Pasha[SUP] 2 [/SUP]
Affiliations
Management of sickle cell disease complications in the setting of the coronavirus disease 2019 (COVID-19) pandemic is complicated with little published pediatric data. We report the first documented case of a 9-year-old boy with sickle cell disease, presenting with fever, cough, and shortness of breath, diagnosed to have acute chest syndrome and coronavirus disease 2019 (COVID-19) pneumonia with inflammatory storm requiring ventilation, exchange blood transfusion, immunomodulatory agents, and prophylactic anticoagulation. The patient responded satisfactorily to the management of the acute illness and was found to be well at the next visit to the pediatric hematology outpatient department following hospital discharge.
Keywords: Sickle cell disease; acute chest syndrome; blood exchange transfusion; enoxaparin; low molecular weight heparin (LMWH); methylprednisolone; severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2/COVID-19).
. 2024 Jul 26:12:2050313X241266436.
doi: 10.1177/2050313X241266436. eCollection 2024. A child with sickle cell disease admitted with coronavirus disease 2019 pneumonia and acute chest syndrome in pediatric intensive care unit: A case report
Mohammad Raza[SUP] 1 [/SUP], Saleh Saad Alshehri[SUP] 2 [/SUP], Mohsina Reshma Pasha[SUP] 2 [/SUP]
Affiliations
- PMID: 39071200
- PMCID: PMC11282508
- DOI: 10.1177/2050313X241266436
Management of sickle cell disease complications in the setting of the coronavirus disease 2019 (COVID-19) pandemic is complicated with little published pediatric data. We report the first documented case of a 9-year-old boy with sickle cell disease, presenting with fever, cough, and shortness of breath, diagnosed to have acute chest syndrome and coronavirus disease 2019 (COVID-19) pneumonia with inflammatory storm requiring ventilation, exchange blood transfusion, immunomodulatory agents, and prophylactic anticoagulation. The patient responded satisfactorily to the management of the acute illness and was found to be well at the next visit to the pediatric hematology outpatient department following hospital discharge.
Keywords: Sickle cell disease; acute chest syndrome; blood exchange transfusion; enoxaparin; low molecular weight heparin (LMWH); methylprednisolone; severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2/COVID-19).