Ronan Kelly
Retired 2020
Week 15: 06.04.2015-12.04.2015
Influenza and ARI morbidity data
Epidemiological data show decrease of influenza and other ARI activity in Russia in comparison with previous week. The nationwide ILI & ARI morbidity level (55.4 per 10 000 of population) was below than the national baseline (68.9) by 19.6%.
ILI and ARI epidemic thresholds were not exceeded in 59 cities collaborating with two WHO NICs in Russia.
... [h=3]Cumulative number of diagnosed influenza cases[/h]
Cumulative results of influenza laboratory diagnosis by different tests were submitted by 56 RBLs and two WHO NICs. According to these data as a result of 2031 patients investigation the overall proportion of respiratory samples positive for influenza virus was estimated as15.8% including 40 (2.0%) influenza A(H1N1)pdm09 cases, 99 (4.9%) influenza A(H3N2) cases, 4 (0.2%) influenza type A and 178 (8/8%) influenza type B cases.
...
[h=3]Conclusion[/h]
Influenza and ARI morbidity data. Decreased influenza and other ARI activity was registered during the week 15.2015 in traditional surveillance system in Russia. The nationwide ILI & ARI morbidity level (55.4 per 10 000 of population) was below than the national baseline (68.9) by 19.6%.
Etiology of ILI & ARI morbidity. The overall proportion of respiratory samples tested positive for influenza virus was estimated as 15.8%. Percent of positive ARI cases of non-influenza etiology (PIV, adeno- and RSV) was estimated as 17.9% of investigated patients by IFA and 19.1% by PCR.
In sentinel surveillance system clinical samples from 77 SARI and ILI/ARI patients were investigated by rRT-PCR. 15 (32.6%) influenza cases were detected including 1 influenza A(H1N1)pdm09 case, 2 influenza A(H3N2) cases and 12 influenza B SARI cases.5 (16.1%) influenza cases were detected including 3 A(H3N2) cases and 2 influenza B ILI/ARI cases.
Antigenic characterization. For the period from the week 40.2014 to week 15.2015 a total 403 influenza viruses were characterized, among them 34 influenza A(H1N1)pdm09, 190 A(H3N2) and 179 influenza B viruses.
20 (58.8%) influenza A(H1N1)pdm09 were antigenically related closely A/California/07/09 reference strain, 14 (41.2%) influenza A(H1N1)pdm09 viruses showed reduced titers (1/8 and more) with antiserum produced against A/California/07/09 virus.
58 (30.5%) influenza A(H3N2) strains were characterized as A/Texas/50/12 like, 132 (69.5%) influenza A(H3N2) strains showed reduced titers (1/8 and more) with antiserum produced against A/Texas/50/12 virus. 18 (37.5%) of 48 influenza A(H3N2) viruses investigated in St.-Petersburg WHO NIC were antigenically similar A/Switzerland/9715293/2013 influenza virus.
Accoding to WHO NIC in Moscow only 3 (2.7%) influenza B viruses were characterized as B/Massachusetts/02/2012 like, 106 (94.6%) influenza type B strains showed redused titers (1/8 and more) with antiserum produced against B/Massachusetts/02/2012 virus. 3 (2.7%) influenza type B strains were characterized as Victoria-lineage viruses and interacted in HI with antiserum prodused against B/Brisbane/60/2008 virus to 1/4 - 1/16 of homologous titers.
All 67 (100%) characterized in in WHO NIC in St.-Petersburg influenza type B viruses were like B/Phuket/3073/13 reference strain.
Genetic characterization: 30 influenza A(H3N2) viruses, 1 influenza A(H1N1)pdm09 virus and 4 influenza type B viruses were investigated. 16 A(H3N2) strains from different sities were shown to be genetically related to clade represented A/Hong-Kong/5738/2014 virus, group 3C.2, subgroup 3C.2a. 14 A(H3N2) viruses from one sity of Siberian FD were shown to be genetically related to clade represented A/Switherland/9715293/2013 virus, group 3C.3, subgroup 3C.3a. 1 influenza A(H1N1)pdm09 virus were related to group 6B represented A/South Africa/3626/2013 virus. 4 influenza type B viruses were related to Yamagata line, clade 3, B/Phuket/3073-like, groupe B/Iceland/78/2014.
Susceptibility to antiviral drugs. Testing of 10 influenza A(H1N1)pdm09 viruses and 12 A(H3N2) viruses showed that al of them were susceptible to oseltamivir but resistance to rimantadine.
http://www.influenza.spb.ru/en/influenza_surveillance_system_in_russia/epidemic_situation/
Influenza and ARI morbidity data
Epidemiological data show decrease of influenza and other ARI activity in Russia in comparison with previous week. The nationwide ILI & ARI morbidity level (55.4 per 10 000 of population) was below than the national baseline (68.9) by 19.6%.
ILI and ARI epidemic thresholds were not exceeded in 59 cities collaborating with two WHO NICs in Russia.
... [h=3]Cumulative number of diagnosed influenza cases[/h]
Cumulative results of influenza laboratory diagnosis by different tests were submitted by 56 RBLs and two WHO NICs. According to these data as a result of 2031 patients investigation the overall proportion of respiratory samples positive for influenza virus was estimated as15.8% including 40 (2.0%) influenza A(H1N1)pdm09 cases, 99 (4.9%) influenza A(H3N2) cases, 4 (0.2%) influenza type A and 178 (8/8%) influenza type B cases.
...
[h=3]Conclusion[/h]
Influenza and ARI morbidity data. Decreased influenza and other ARI activity was registered during the week 15.2015 in traditional surveillance system in Russia. The nationwide ILI & ARI morbidity level (55.4 per 10 000 of population) was below than the national baseline (68.9) by 19.6%.
Etiology of ILI & ARI morbidity. The overall proportion of respiratory samples tested positive for influenza virus was estimated as 15.8%. Percent of positive ARI cases of non-influenza etiology (PIV, adeno- and RSV) was estimated as 17.9% of investigated patients by IFA and 19.1% by PCR.
In sentinel surveillance system clinical samples from 77 SARI and ILI/ARI patients were investigated by rRT-PCR. 15 (32.6%) influenza cases were detected including 1 influenza A(H1N1)pdm09 case, 2 influenza A(H3N2) cases and 12 influenza B SARI cases.5 (16.1%) influenza cases were detected including 3 A(H3N2) cases and 2 influenza B ILI/ARI cases.
Antigenic characterization. For the period from the week 40.2014 to week 15.2015 a total 403 influenza viruses were characterized, among them 34 influenza A(H1N1)pdm09, 190 A(H3N2) and 179 influenza B viruses.
20 (58.8%) influenza A(H1N1)pdm09 were antigenically related closely A/California/07/09 reference strain, 14 (41.2%) influenza A(H1N1)pdm09 viruses showed reduced titers (1/8 and more) with antiserum produced against A/California/07/09 virus.
58 (30.5%) influenza A(H3N2) strains were characterized as A/Texas/50/12 like, 132 (69.5%) influenza A(H3N2) strains showed reduced titers (1/8 and more) with antiserum produced against A/Texas/50/12 virus. 18 (37.5%) of 48 influenza A(H3N2) viruses investigated in St.-Petersburg WHO NIC were antigenically similar A/Switzerland/9715293/2013 influenza virus.
Accoding to WHO NIC in Moscow only 3 (2.7%) influenza B viruses were characterized as B/Massachusetts/02/2012 like, 106 (94.6%) influenza type B strains showed redused titers (1/8 and more) with antiserum produced against B/Massachusetts/02/2012 virus. 3 (2.7%) influenza type B strains were characterized as Victoria-lineage viruses and interacted in HI with antiserum prodused against B/Brisbane/60/2008 virus to 1/4 - 1/16 of homologous titers.
All 67 (100%) characterized in in WHO NIC in St.-Petersburg influenza type B viruses were like B/Phuket/3073/13 reference strain.
Genetic characterization: 30 influenza A(H3N2) viruses, 1 influenza A(H1N1)pdm09 virus and 4 influenza type B viruses were investigated. 16 A(H3N2) strains from different sities were shown to be genetically related to clade represented A/Hong-Kong/5738/2014 virus, group 3C.2, subgroup 3C.2a. 14 A(H3N2) viruses from one sity of Siberian FD were shown to be genetically related to clade represented A/Switherland/9715293/2013 virus, group 3C.3, subgroup 3C.3a. 1 influenza A(H1N1)pdm09 virus were related to group 6B represented A/South Africa/3626/2013 virus. 4 influenza type B viruses were related to Yamagata line, clade 3, B/Phuket/3073-like, groupe B/Iceland/78/2014.
Susceptibility to antiviral drugs. Testing of 10 influenza A(H1N1)pdm09 viruses and 12 A(H3N2) viruses showed that al of them were susceptible to oseltamivir but resistance to rimantadine.
http://www.influenza.spb.ru/en/influenza_surveillance_system_in_russia/epidemic_situation/