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Risk factors for severe complications of the novel influenza A (H1N1): analysis of patients hospitalized in Italy

tetano

Editor, Senior Moderator
RESEARCH NOTE
Risk factors for severe complications of the novel influenza A (H1N1): analysis of patients hospitalized in Italy
M. Bassetti 1 , A. Parisini 1 , A. Calzi 1 , F. M. Bobbio Pallavicini 2 , G. Cassola 3 , S. Artioli 4 , M. Anselmo 5 , G. Pagano 6 , G. Rezza 7 and C. Viscoli 1 for the Ligurian H1N1 Collaborative Group
1) Infectious Diseases Division, San Martino Hospital and University of Genoa School of Medicine, Genoa , 2) Intensive Care Unit, San Martino Hospital, Genoa , 3) Infectious Diseases Division, EO Galliera, Genova , 4) Infectious Diseases Division, S. Andrea Hospital, Spezia , 5) Infectious Diseases Division, San Paolo Hospital, Savona , 6) Infectious Diseases Division, S. Martino Hospital, Genova and 7) Department of Infectious Diseases, Istituto Superiore di Sanit?, Roma, Italy
Corresponding author and reprint requests: M. Bassetti, Clinica Malattie Infettive, AOU San Martino, L.go R.Benzi 10, 16132 Genova, Italy




ABSTRACT

Eighty-one patients affected by the novel influenza A (H1N1), hospitalized in North-western Italy, were studied. The median age was 32 years (range 1?81 years). Fifty-six (69%) had an underlying medical condition, including lung disorders (asthma or chronic obstructive pulmonary disease) in 34% and obesity in 25%. Fifty percent of them had pneumonia, 12% were admitted to the intensive care unit and 3% died. Antiviral treatment was initiated in 75% of patients started within 48 h. Older age and lung and neurocognitive disorders were associated with severe disease and death.


http://www3.interscience.wiley.com/journal/123488773/abstract?CRETRY=1&SRETRY=0
 
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