tetano
Editor, Senior Moderator
Rheumatol Int. 2020 Apr 20. doi: 10.1007/s00296-020-04584-7. [Epub ahead of print]
Coronavirus Disease 19 (COVID-19) complicated with pneumonia in a patient with rheumatoid arthritis receiving conventional disease-modifying antirheumatic drugs.
Song J[SUP]1[/SUP], Kang S[SUP]1[/SUP], Choi SW[SUP]1[/SUP], Seo KW[SUP]2[/SUP], Lee S[SUP]3[/SUP], So MW[SUP]4[/SUP], Lim DH[SUP]5[/SUP].
Author information
Abstract
In December 2019, numerous coronavirus disease 2019 (COVID-19) cases were reported in Wuhan, China, which has since spread throughout the world. However, its impact on rheumatoid arthritis (RA) patients is unknown. Herein, we report a case of COVID-19 pneumonia in a 61-year-old female RA patient who was receiving conventional disease-modifying antirheumatic drugs (cDMARDs). The patient presented with a 4-day history of myalgia and febrile sensation. COVID-19 was confirmed by real-time polymerase chain reaction (PCR). Chest X-ray showed increased opacity on the right lower lung area, and C-reactive protein level was slightly elevated. The patient was treated with antiviral agents (lopinavir/ritonavir), and treatment with cDMARDs was discontinued except hydroxychloroquine. Her symptoms and laboratory results gradually improved. Three weeks later, real-time PCR for COVID-19 showed negative conversion, and the patient was discharged without any complications.
KEYWORDS:
COVID-19; Coronavirus; Disease-modifying antirheumatic drugs; Pneumonia; Rheumatoid arthritis
PMID:32314010DOI:10.1007/s00296-020-04584-7
Coronavirus Disease 19 (COVID-19) complicated with pneumonia in a patient with rheumatoid arthritis receiving conventional disease-modifying antirheumatic drugs.
Song J[SUP]1[/SUP], Kang S[SUP]1[/SUP], Choi SW[SUP]1[/SUP], Seo KW[SUP]2[/SUP], Lee S[SUP]3[/SUP], So MW[SUP]4[/SUP], Lim DH[SUP]5[/SUP].
Author information
Abstract
In December 2019, numerous coronavirus disease 2019 (COVID-19) cases were reported in Wuhan, China, which has since spread throughout the world. However, its impact on rheumatoid arthritis (RA) patients is unknown. Herein, we report a case of COVID-19 pneumonia in a 61-year-old female RA patient who was receiving conventional disease-modifying antirheumatic drugs (cDMARDs). The patient presented with a 4-day history of myalgia and febrile sensation. COVID-19 was confirmed by real-time polymerase chain reaction (PCR). Chest X-ray showed increased opacity on the right lower lung area, and C-reactive protein level was slightly elevated. The patient was treated with antiviral agents (lopinavir/ritonavir), and treatment with cDMARDs was discontinued except hydroxychloroquine. Her symptoms and laboratory results gradually improved. Three weeks later, real-time PCR for COVID-19 showed negative conversion, and the patient was discharged without any complications.
KEYWORDS:
COVID-19; Coronavirus; Disease-modifying antirheumatic drugs; Pneumonia; Rheumatoid arthritis
PMID:32314010DOI:10.1007/s00296-020-04584-7