tetano
Editor, Senior Moderator
Rev Soc Bras Med Trop
. 2021 Nov 12;54:e0383.
doi: 10.1590/0037-8682-0383-2021. eCollection 2021.
Systemic inflammatory syndrome in children during COVID-19 pandemic in Ceará state, northeastern Brazil: an observational study
Luís Arthur Brasil Gadelha Farias[SUP] 1 [/SUP], Magda Moura de Almeida[SUP] 2 3 [/SUP], Pâmela Maria Costa Linhares[SUP] 2 [/SUP], Bruno Cavalcante Fales de Brito Alves[SUP] 4 [/SUP], Roberto Jorge Colares Duarte Filho[SUP] 3 [/SUP], Roberio Dias Leite[SUP] 1 3 [/SUP], Marco Aurelio Palazzi Safadi[SUP] 5 [/SUP], Luciano Pamplona de Góes Cavalcanti[SUP] 3 4 [/SUP]
Affiliations
Abstract
In this study, we report the occurrence of multisystemic inflammatory syndrome among 64 children (2 deaths) with recent severe acute respiratory syndrome-related coronavirus 2 (SARS-COV-2) infections in the northeast region of Brazil. The major clinical symptoms and signs reported were exanthema (60.9%), abdominal pain (56.3%), nausea and vomiting (46.9%), diarrhea (37.5%), and dyspnea (37.5%). Laboratory findings revealed that the levels of C-reactive protein (75.0%), hemoglobin (51.6%), D-dimer (48.4%), lymphocytes (43.8%), LDH (45.3%), AST (42.2%), ALT (51.6%), and ferritin (48.4%) were above the reference values for a given age and gender. The clinical findings were similar to those observed in Kawasaki disease, although it represents a separate entity, emphasizing the need for proactive surveillance and early treatment.
. 2021 Nov 12;54:e0383.
doi: 10.1590/0037-8682-0383-2021. eCollection 2021.
Systemic inflammatory syndrome in children during COVID-19 pandemic in Ceará state, northeastern Brazil: an observational study
Luís Arthur Brasil Gadelha Farias[SUP] 1 [/SUP], Magda Moura de Almeida[SUP] 2 3 [/SUP], Pâmela Maria Costa Linhares[SUP] 2 [/SUP], Bruno Cavalcante Fales de Brito Alves[SUP] 4 [/SUP], Roberto Jorge Colares Duarte Filho[SUP] 3 [/SUP], Roberio Dias Leite[SUP] 1 3 [/SUP], Marco Aurelio Palazzi Safadi[SUP] 5 [/SUP], Luciano Pamplona de Góes Cavalcanti[SUP] 3 4 [/SUP]
Affiliations
- PMID: 34787262
- DOI: 10.1590/0037-8682-0383-2021
Abstract
In this study, we report the occurrence of multisystemic inflammatory syndrome among 64 children (2 deaths) with recent severe acute respiratory syndrome-related coronavirus 2 (SARS-COV-2) infections in the northeast region of Brazil. The major clinical symptoms and signs reported were exanthema (60.9%), abdominal pain (56.3%), nausea and vomiting (46.9%), diarrhea (37.5%), and dyspnea (37.5%). Laboratory findings revealed that the levels of C-reactive protein (75.0%), hemoglobin (51.6%), D-dimer (48.4%), lymphocytes (43.8%), LDH (45.3%), AST (42.2%), ALT (51.6%), and ferritin (48.4%) were above the reference values for a given age and gender. The clinical findings were similar to those observed in Kawasaki disease, although it represents a separate entity, emphasizing the need for proactive surveillance and early treatment.