tetano
Editor, Senior Moderator
Rev Soc Bras Med Trop
. 2021 Mar 22;54:e0878.
doi: 10.1590/0037-8682-0878-2020. eCollection 2021.
Risk factors associated with mortality in patients hospitalized for coronavirus disease 2019 in Rio de Janeiro, Brazil
Julio C?sar Delgado Correal[SUP] 1 [/SUP], Victor Edgar Fiestas Sol?rzano[SUP] 2 [/SUP], Paula Hesselberg Damasco[SUP] 3 [/SUP], Maria de Lourdes Martins[SUP] 1 [/SUP], Adriana Guerreiro Soares de Oliveira[SUP] 1 [/SUP], Carla Salles Campos[SUP] 1 [/SUP], Marcos Fernando Fornasari[SUP] 1 [/SUP], Elzinandes Leal de Azeredo[SUP] 2 [/SUP], Paulo Vieira Damasco[SUP] 4 5 [/SUP]
Affiliations
Abstract
Introduction: Understanding the mortality-associated risk factors of coronavirus disease 2019 will impact clinical decisions.
Methods: This retrospective longitudinal study included patients hospitalized for coronavirus disease in Rio de Janeiro, Brazil. The Kaplan-Meier method and multivariate Cox regression analysis were used.
Results: Sequential Organ Failure Assessment score of ?2 (hazard ratio 4.614; 95% confidence interval =2.210-9.634; p<0.001) and neutrophil/lymphocyte ratio of >5 (hazard ratio=2.616; 95% confidence interval=1.303-5.252; p=0.007) were independently associated with mortality.
Conclusions: Sequential Organ Failure Assessment score and neutrophil/lymphocyte ratio on admission can identify coronavirus disease patients at increased risk of death and guide subsequent clinical decisions.
. 2021 Mar 22;54:e0878.
doi: 10.1590/0037-8682-0878-2020. eCollection 2021.
Risk factors associated with mortality in patients hospitalized for coronavirus disease 2019 in Rio de Janeiro, Brazil
Julio C?sar Delgado Correal[SUP] 1 [/SUP], Victor Edgar Fiestas Sol?rzano[SUP] 2 [/SUP], Paula Hesselberg Damasco[SUP] 3 [/SUP], Maria de Lourdes Martins[SUP] 1 [/SUP], Adriana Guerreiro Soares de Oliveira[SUP] 1 [/SUP], Carla Salles Campos[SUP] 1 [/SUP], Marcos Fernando Fornasari[SUP] 1 [/SUP], Elzinandes Leal de Azeredo[SUP] 2 [/SUP], Paulo Vieira Damasco[SUP] 4 5 [/SUP]
Affiliations
- PMID: 33759936
- DOI: 10.1590/0037-8682-0878-2020
Abstract
Introduction: Understanding the mortality-associated risk factors of coronavirus disease 2019 will impact clinical decisions.
Methods: This retrospective longitudinal study included patients hospitalized for coronavirus disease in Rio de Janeiro, Brazil. The Kaplan-Meier method and multivariate Cox regression analysis were used.
Results: Sequential Organ Failure Assessment score of ?2 (hazard ratio 4.614; 95% confidence interval =2.210-9.634; p<0.001) and neutrophil/lymphocyte ratio of >5 (hazard ratio=2.616; 95% confidence interval=1.303-5.252; p=0.007) were independently associated with mortality.
Conclusions: Sequential Organ Failure Assessment score and neutrophil/lymphocyte ratio on admission can identify coronavirus disease patients at increased risk of death and guide subsequent clinical decisions.