tetano
Editor, Senior Moderator
Rev Paul Pediatr
. 2020;38:e2020165.
doi: 10.1590/1984-0462/2020/38/2020165. Epub 2020 Aug 26.
MULTISYSTEM INFLAMMATORY SYNDROME IN A CHILD ASSOCIATED WITH CORONAVIRUS DISEASE 19 IN THE BRAZILIAN AMAZON: FATAL OUTCOME IN AN INFANT
[Article in Portuguese, En]
Emmerson Carlos Franco de Farias[SUP] 1 [/SUP], Maria Cleonice Aguiar Justino[SUP] 2 [/SUP], Mary Lucy Ferraz Maia Fiuza de Mello[SUP] 1 [/SUP]
Affiliations
Abstract
Objective: Recently, there have been reports of children with severe inflammatory syndrome and multiorgan dysfunction associated with elevated inflammatory markers. These cases are reported as presenting the Multisystem Inflammatory Syndrome in Children (MIS-C) associated with COVID-19. In this study, we describe with parental permission a case of MIS-C in an infant with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.
Case description: A seven-month-old infant, with SARS-CoV-2 infection and a history of extreme preterm birth and very low weight at birth, with an initial course of mild respiratory symptoms and abrupt progression to vasoplegic shock, myocarditis and hyperinflammation syndrome, shown by high levels of troponin I, ferritin, CRP, D-dimer and hypoalbuminemia. Despite the intensive care provided, the child developed multiple organ dysfunction and died.
Comments: Patients with a history of extreme prematurity may present with MIS-C in the presence of COVID-19 and are a group of special concern.
. 2020;38:e2020165.
doi: 10.1590/1984-0462/2020/38/2020165. Epub 2020 Aug 26.
MULTISYSTEM INFLAMMATORY SYNDROME IN A CHILD ASSOCIATED WITH CORONAVIRUS DISEASE 19 IN THE BRAZILIAN AMAZON: FATAL OUTCOME IN AN INFANT
[Article in Portuguese, En]
Emmerson Carlos Franco de Farias[SUP] 1 [/SUP], Maria Cleonice Aguiar Justino[SUP] 2 [/SUP], Mary Lucy Ferraz Maia Fiuza de Mello[SUP] 1 [/SUP]
Affiliations
- PMID: 32876282
- DOI: 10.1590/1984-0462/2020/38/2020165
Abstract
Objective: Recently, there have been reports of children with severe inflammatory syndrome and multiorgan dysfunction associated with elevated inflammatory markers. These cases are reported as presenting the Multisystem Inflammatory Syndrome in Children (MIS-C) associated with COVID-19. In this study, we describe with parental permission a case of MIS-C in an infant with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.
Case description: A seven-month-old infant, with SARS-CoV-2 infection and a history of extreme preterm birth and very low weight at birth, with an initial course of mild respiratory symptoms and abrupt progression to vasoplegic shock, myocarditis and hyperinflammation syndrome, shown by high levels of troponin I, ferritin, CRP, D-dimer and hypoalbuminemia. Despite the intensive care provided, the child developed multiple organ dysfunction and died.
Comments: Patients with a history of extreme prematurity may present with MIS-C in the presence of COVID-19 and are a group of special concern.