tetano
Editor, Senior Moderator
Rev Neurosci
. 2020 May 28;/j/revneuro.ahead-of-print/revneuro-2020-0026/revneuro-2020-0026.xml.
doi: 10.1515/revneuro-2020-0026. Online ahead of print.
The Involvement of the Central Nervous System in Patients With COVID-19
Kiarash Saleki[SUP] 1 [/SUP], Mohammad Banazadeh[SUP] 1 [/SUP], Amene Saghazadeh[SUP] 1 2 [/SUP], Nima Rezaei[SUP] 2 3 4 [/SUP]
Affiliations
Abstract
Coronaviruses disease (COVID-19) has caused major outbreaks. A novel variant, SARS-CoV-2, is responsible for COVID-19 pandemic. Clinical presentations and pathological mechanisms of COVID-19 are broad. The respiratory aspect of the disease has been extensively researched. Emerging studies point out the possibility of the central nervous system (CNS) involvement by COVID-19. Here, we discuss the current evidence for CNS involvement in COVID-19 and highlight that the high pathogenicity of SARS-CoV-2 might be due to its neuroinvasive potential.
Keywords: ACE2; COVID-19; SARS-CoV-2; anosmia; central nervous system (CNS); coronavirus.
. 2020 May 28;/j/revneuro.ahead-of-print/revneuro-2020-0026/revneuro-2020-0026.xml.
doi: 10.1515/revneuro-2020-0026. Online ahead of print.
The Involvement of the Central Nervous System in Patients With COVID-19
Kiarash Saleki[SUP] 1 [/SUP], Mohammad Banazadeh[SUP] 1 [/SUP], Amene Saghazadeh[SUP] 1 2 [/SUP], Nima Rezaei[SUP] 2 3 4 [/SUP]
Affiliations
- PMID: 32463395
- DOI: 10.1515/revneuro-2020-0026
Abstract
Coronaviruses disease (COVID-19) has caused major outbreaks. A novel variant, SARS-CoV-2, is responsible for COVID-19 pandemic. Clinical presentations and pathological mechanisms of COVID-19 are broad. The respiratory aspect of the disease has been extensively researched. Emerging studies point out the possibility of the central nervous system (CNS) involvement by COVID-19. Here, we discuss the current evidence for CNS involvement in COVID-19 and highlight that the high pathogenicity of SARS-CoV-2 might be due to its neuroinvasive potential.
Keywords: ACE2; COVID-19; SARS-CoV-2; anosmia; central nervous system (CNS); coronavirus.