tetano
Editor, Senior Moderator
Rev Med Virol
. 2020 Aug 28;e2159.
doi: 10.1002/rmv.2159. Online ahead of print.
Vitamin D and Covid-19: From potential therapeutic effects to unanswered questions
Majid Teymoori-Rad[SUP] 1 [/SUP], Sayed Mahdi Marashi[SUP] 1 [/SUP]
Affiliations
Abstract
Evidence suggests that vitamin D supplementation could potentially be effective either in treatment or prevention of coronavirus disease 2019 (Covid-19). Indeed, several studies and trials have begun to investigate the impact of vitamin D supplementation on patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. In this review, we focus on the potential mechanisms of vitamin D in the pathogenesis of Covid-19. We consider whether deficiency of vitamin D may be one of the underlying biological factors that could explain the excess mortality seen among non-Caucasians. We also raise several important questions which need to be addressed to provide a clear picture of the extent to which vitamin D supplementation may benefit patients with Covid-19, particularly those with underlying risk factors.
Keywords: COVID-19; Vitamin D; immune response.
. 2020 Aug 28;e2159.
doi: 10.1002/rmv.2159. Online ahead of print.
Vitamin D and Covid-19: From potential therapeutic effects to unanswered questions
Majid Teymoori-Rad[SUP] 1 [/SUP], Sayed Mahdi Marashi[SUP] 1 [/SUP]
Affiliations
- PMID: 32856339
- DOI: 10.1002/rmv.2159
Abstract
Evidence suggests that vitamin D supplementation could potentially be effective either in treatment or prevention of coronavirus disease 2019 (Covid-19). Indeed, several studies and trials have begun to investigate the impact of vitamin D supplementation on patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. In this review, we focus on the potential mechanisms of vitamin D in the pathogenesis of Covid-19. We consider whether deficiency of vitamin D may be one of the underlying biological factors that could explain the excess mortality seen among non-Caucasians. We also raise several important questions which need to be addressed to provide a clear picture of the extent to which vitamin D supplementation may benefit patients with Covid-19, particularly those with underlying risk factors.
Keywords: COVID-19; Vitamin D; immune response.