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Rev Med Virol . Passive immunotherapies for the next influenza pandemic

tetano

Editor, Senior Moderator
Rev Med Virol


. 2024 May;34(3):e2533.
doi: 10.1002/rmv.2533. Passive immunotherapies for the next influenza pandemic

Daniele Focosi[SUP] 1 [/SUP], Massimo Franchini[SUP] 2 [/SUP], Jonathon W Senefeld[SUP] 3 4 [/SUP], Michael J Joyner[SUP] 3 [/SUP], David J Sullivan[SUP] 5 [/SUP], Andrew Pekosz[SUP] 5 [/SUP], Fabrizio Maggi[SUP] 6 [/SUP], Arturo Casadevall[SUP] 5 [/SUP]



Affiliations
Abstract

Influenzavirus is among the most relevant candidates for a next pandemic. We review here the phylogeny of former influenza pandemics, and discuss candidate lineages. After briefly reviewing the other existing antiviral options, we discuss in detail the evidences supporting the efficacy of passive immunotherapies against influenzavirus, with a focus on convalescent plasma.

Keywords: H1N1pdm09; H5N1; H7N9; bird fu; convalescent plasma; influenza virus; pandemic influenza; swine flu.

 
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