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Rev Clin Esp . Does the Maternal-Fetal Transmission of SARS-CoV-2 Occur During Pregnancy?

tetano

Editor, Senior Moderator
Rev Clin Esp


. 2020 Jun 5;S0014-2565(20)30156-9.
doi: 10.1016/j.rce.2020.06.001. Online ahead of print.
Does the Maternal-Fetal Transmission of SARS-CoV-2 Occur During Pregnancy?


[Article in English, Spanish]

J J Hijona El?segui[SUP] 1 [/SUP], A L Carballo Garc?a[SUP] 2 [/SUP], A C Fern?ndez Risquez[SUP] 2 [/SUP], M Berm?dez Quintana[SUP] 2 [/SUP], J F Exp?sito Montes[SUP] 3 [/SUP]



Affiliations

Abstract

Background and objective: On January 7[SUP]th[/SUP], 2020, a new coronavirus, SARS-CoV-2, was identified, as responsible for a new human disease: COVID-19. Given its recent appearance, our current knowledge about the possible influence that this disease can exert on pregnancy is very limited. One of the unknowns to be solved is whether there is a vertical transmission of the infection during pregnancy.
Patients and methods: Using the Real-time Polymerase Chain Reaction techniques for SARS-CoV-2 nucleic acids, the possible presence of this germ in vaginal discharge and amniotic fluid was investigated in four pregnant Caucasian patients affected by mild acute symptoms of COVID-19 during the second trimester of pregnancy.
Results: There is no laboratory evidence to suggest a possible passage of SARS-CoV-2 from the infected mother to the amniotic fluid.
Conclusions: It is necessary to expand the investigation of COVID-19 cases diagnosed during pregnancy to clarify the real influence that SARS-CoV-2 has on pregnant women and their offspring, as well as those factors that modulate the disease.

Keywords: Amniotic fluid; COVID-19; Coronavirus; Embarazo; L?quido amni?tico; Perinatal; Pregnancy; Transmisi?n vertical; Vertical transmission.
 
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