tetano
Editor, Senior Moderator
Pathogens. 2016 Aug 10;5(3). pii: E55. doi: 10.3390/pathogens5030055.
[h=1]Retrospective Analysis of the Equine Influenza Virus A/Equine/Kirgizia/26/1974 (H7N7) Isolated in Central Asia.[/h] Karamendin K[SUP]1[/SUP], Kydyrmanov A[SUP]2[/SUP], Sayatov M[SUP]3[/SUP], Strochkov V[SUP]4[/SUP], Sandybayev N[SUP]5[/SUP], Sultankulova K[SUP]6[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] A retrospective phylogenetic characterization of the hemagglutinin, neuraminidase and nucleoprotein genes of equine influenza virus A/equine/Kirgizia/26/1974 (H7N7) which caused an outbreak in Kirgizia (a former Soviet Union republic, now Kyrgyzstan) in 1977 was conducted. It was defined that it was closely related to the strain London/1973 isolated in Europe and it shared a maximum nucleotide sequence identity at 99% with it. This Central Asian equine influenza virus isolate did not have any specific genetic signatures and can be considered as an epizootic strain of 1974 that spread in Europe. The absence of antibodies to this subtype EI virus (EIV) in recent research confirms its disappearance as of the 1990s when the antibodies were last found in unvaccinated horses.
[h=4]KEYWORDS:[/h] Central Asia; H7N7; equine influenza; phylogeny; sequence
PMID: 27517962 DOI: 10.3390/pathogens5030055
[PubMed]
[h=1]Retrospective Analysis of the Equine Influenza Virus A/Equine/Kirgizia/26/1974 (H7N7) Isolated in Central Asia.[/h] Karamendin K[SUP]1[/SUP], Kydyrmanov A[SUP]2[/SUP], Sayatov M[SUP]3[/SUP], Strochkov V[SUP]4[/SUP], Sandybayev N[SUP]5[/SUP], Sultankulova K[SUP]6[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] A retrospective phylogenetic characterization of the hemagglutinin, neuraminidase and nucleoprotein genes of equine influenza virus A/equine/Kirgizia/26/1974 (H7N7) which caused an outbreak in Kirgizia (a former Soviet Union republic, now Kyrgyzstan) in 1977 was conducted. It was defined that it was closely related to the strain London/1973 isolated in Europe and it shared a maximum nucleotide sequence identity at 99% with it. This Central Asian equine influenza virus isolate did not have any specific genetic signatures and can be considered as an epizootic strain of 1974 that spread in Europe. The absence of antibodies to this subtype EI virus (EIV) in recent research confirms its disappearance as of the 1990s when the antibodies were last found in unvaccinated horses.
[h=4]KEYWORDS:[/h] Central Asia; H7N7; equine influenza; phylogeny; sequence
PMID: 27517962 DOI: 10.3390/pathogens5030055
[PubMed]