tetano
Editor, Senior Moderator
Respirol Case Rep
. 2021 Jun 8;9(7):e00801.
doi: 10.1002/rcr2.801. eCollection 2021 Jul.
Fatal cytomegalovirus pneumonia in a critically ill patient with COVID-19
Saori Amiya[SUP] 1 [/SUP], Haruhiko Hirata[SUP] 1 [/SUP], Takayuki Shiroyama[SUP] 1 [/SUP], Yuichi Adachi[SUP] 1 [/SUP], Takayuki Niitsu[SUP] 1 [/SUP], Yoshimi Noda[SUP] 1 [/SUP], Takatoshi Enomoto[SUP] 1 [/SUP], Reina Hara[SUP] 1 [/SUP], Kiyoharu Fukushima[SUP] 1 [/SUP], Yasuhiko Suga[SUP] 1 [/SUP], Kotaro Miyake[SUP] 1 [/SUP], Moe Koide[SUP] 2 [/SUP], Akinori Uchiyama[SUP] 2 [/SUP], Yoshito Takeda[SUP] 1 [/SUP], Atsushi Kumanogoh[SUP] 1 [/SUP]
Affiliations
Abstract
Coronavirus disease 2019 (COVID-19) can cause severe lymphopenia and respiratory failure requiring prolonged invasive mechanical ventilation (MV). COVID-19 patients with severe lymphopenia or respiratory failure are at risk of developing secondary infections. Here, we present the needle autopsy findings of a critically ill patient with COVID-19 who required reintubation and prolonged MV, and eventually died of secondary cytomegalovirus (CMV) pneumonia. This case highlights the potential risk of long-term steroid use and the need for routine monitoring for CMV infection in critically ill patients with COVID-19.
Keywords: COVID‐19; Co‐infection; corticosteroid therapy; cytomegalovirus pneumonia; lymphopenia.
. 2021 Jun 8;9(7):e00801.
doi: 10.1002/rcr2.801. eCollection 2021 Jul.
Fatal cytomegalovirus pneumonia in a critically ill patient with COVID-19
Saori Amiya[SUP] 1 [/SUP], Haruhiko Hirata[SUP] 1 [/SUP], Takayuki Shiroyama[SUP] 1 [/SUP], Yuichi Adachi[SUP] 1 [/SUP], Takayuki Niitsu[SUP] 1 [/SUP], Yoshimi Noda[SUP] 1 [/SUP], Takatoshi Enomoto[SUP] 1 [/SUP], Reina Hara[SUP] 1 [/SUP], Kiyoharu Fukushima[SUP] 1 [/SUP], Yasuhiko Suga[SUP] 1 [/SUP], Kotaro Miyake[SUP] 1 [/SUP], Moe Koide[SUP] 2 [/SUP], Akinori Uchiyama[SUP] 2 [/SUP], Yoshito Takeda[SUP] 1 [/SUP], Atsushi Kumanogoh[SUP] 1 [/SUP]
Affiliations
- PMID: 34136262
- PMCID: PMC8185623
- DOI: 10.1002/rcr2.801
Abstract
Coronavirus disease 2019 (COVID-19) can cause severe lymphopenia and respiratory failure requiring prolonged invasive mechanical ventilation (MV). COVID-19 patients with severe lymphopenia or respiratory failure are at risk of developing secondary infections. Here, we present the needle autopsy findings of a critically ill patient with COVID-19 who required reintubation and prolonged MV, and eventually died of secondary cytomegalovirus (CMV) pneumonia. This case highlights the potential risk of long-term steroid use and the need for routine monitoring for CMV infection in critically ill patients with COVID-19.
Keywords: COVID‐19; Co‐infection; corticosteroid therapy; cytomegalovirus pneumonia; lymphopenia.