tetano
Editor, Senior Moderator
Respir Res. 2020 Apr 22;21(1):96. doi: 10.1186/s12931-020-01363-7.
The unsynchronized changes of CT image and nucleic acid detection in COVID-19: reports the two cases from Gansu, China.
Gao J[SUP]1,[/SUP][SUP]2,[/SUP][SUP]3[/SUP], Liu JQ[SUP]4[/SUP], Wen HJ[SUP]5[/SUP], Liu H[SUP]1[/SUP], Hu WD[SUP]1[/SUP], Han X[SUP]6[/SUP], Li CX[SUP]2[/SUP], Wang XJ[SUP]7[/SUP].
Author information
Abstract
The novel coronavirus disease (COVID-19) outbreak started in December 2019 in Wuhan, China, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The CT image is used to assess the disease progress, whereas the continued two times of negative results from SARS-CoV-2 nucleic acid detection had been considered as a criterion for ending antiviral treatment. We compared the two COVID-19 cases with similar backgrounds and CT image repeated intervals under treatment. Our report highlighted the unsynchronized expression in the changes of CT image and nucleic acid detection in COVID-19, and lasting positive nucleic acid test result in patients recovered from pneumonia. It may be contributed to recognize the disease and improve prevention.
KEYWORDS:
COVID-19; CT image; Nucleic acid detection; SARS-CoV-2
PMID:32321530DOI:10.1186/s12931-020-01363-7
The unsynchronized changes of CT image and nucleic acid detection in COVID-19: reports the two cases from Gansu, China.
Gao J[SUP]1,[/SUP][SUP]2,[/SUP][SUP]3[/SUP], Liu JQ[SUP]4[/SUP], Wen HJ[SUP]5[/SUP], Liu H[SUP]1[/SUP], Hu WD[SUP]1[/SUP], Han X[SUP]6[/SUP], Li CX[SUP]2[/SUP], Wang XJ[SUP]7[/SUP].
Author information
Abstract
The novel coronavirus disease (COVID-19) outbreak started in December 2019 in Wuhan, China, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The CT image is used to assess the disease progress, whereas the continued two times of negative results from SARS-CoV-2 nucleic acid detection had been considered as a criterion for ending antiviral treatment. We compared the two COVID-19 cases with similar backgrounds and CT image repeated intervals under treatment. Our report highlighted the unsynchronized expression in the changes of CT image and nucleic acid detection in COVID-19, and lasting positive nucleic acid test result in patients recovered from pneumonia. It may be contributed to recognize the disease and improve prevention.
KEYWORDS:
COVID-19; CT image; Nucleic acid detection; SARS-CoV-2
PMID:32321530DOI:10.1186/s12931-020-01363-7