tetano
Editor, Senior Moderator
Respir Res
. 2020 Oct 30;21(1):286.
doi: 10.1186/s12931-020-01550-6.
Are there pulmonary sequelae in patients recovering from COVID-19?
Paola Rogliani[SUP] 1 2 [/SUP], Luigino Calzetta[SUP] 3 [/SUP], Angelo Coppola[SUP] 4 [/SUP], Ermanno Puxeddu[SUP] 4 5 [/SUP], Gianluigi Sergiacomi[SUP] 6 [/SUP], Dejanira D'Amato[SUP] 6 [/SUP], Antonio Orlacchio[SUP] 7 8 [/SUP]
Affiliations
Abstract
It has been recently hypothesized that infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may lead to fibrotic sequelae in patients recovering from coronavirus disease 2019 (COVID-19). In this observational study, hospitalized patients with COVID-19 had a HRCT of the chest performed to detect the extension of fibrotic abnormalities via Hounsfield Units (HU). At follow-up, the lung density significantly improved in both lungs and in each lobe of all patients, being in the normal range (- 950 to - 700 HU). This study provides preliminary evidence that hospitalized patients with mild-to-moderate forms of COVID-19 are not at risk of developing pulmonary fibrosis.
Keywords: COVID-19; HRCT; Pulmonary fibrosis.
. 2020 Oct 30;21(1):286.
doi: 10.1186/s12931-020-01550-6.
Are there pulmonary sequelae in patients recovering from COVID-19?
Paola Rogliani[SUP] 1 2 [/SUP], Luigino Calzetta[SUP] 3 [/SUP], Angelo Coppola[SUP] 4 [/SUP], Ermanno Puxeddu[SUP] 4 5 [/SUP], Gianluigi Sergiacomi[SUP] 6 [/SUP], Dejanira D'Amato[SUP] 6 [/SUP], Antonio Orlacchio[SUP] 7 8 [/SUP]
Affiliations
- PMID: 33126869
- DOI: 10.1186/s12931-020-01550-6
Abstract
It has been recently hypothesized that infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may lead to fibrotic sequelae in patients recovering from coronavirus disease 2019 (COVID-19). In this observational study, hospitalized patients with COVID-19 had a HRCT of the chest performed to detect the extension of fibrotic abnormalities via Hounsfield Units (HU). At follow-up, the lung density significantly improved in both lungs and in each lobe of all patients, being in the normal range (- 950 to - 700 HU). This study provides preliminary evidence that hospitalized patients with mild-to-moderate forms of COVID-19 are not at risk of developing pulmonary fibrosis.
Keywords: COVID-19; HRCT; Pulmonary fibrosis.