tetano
Editor, Senior Moderator
Respir Investig
. 2021 Jan 21;S2212-5345(21)00002-2.
doi: 10.1016/j.resinv.2020.12.005. Online ahead of print.
Sustained coronavirus disease 2019-related organizing pneumonia successfully treated with corticosteroid
Hiroshi Takumida[SUP] 1 [/SUP], Shinyu Izumi[SUP] 2 [/SUP], Keita Sakamoto[SUP] 2 [/SUP], Masao Hashimoto[SUP] 2 [/SUP], Satoru Ishii[SUP] 2 [/SUP], Manabu Suzuki[SUP] 2 [/SUP], Jin Takasaki[SUP] 2 [/SUP], Mariko Tanaka[SUP] 3 [/SUP], Toru Igari[SUP] 4 [/SUP], Masayuki Hojo[SUP] 2 [/SUP]
Affiliations
Abstract
A 70-year-old Japanese man contracted severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and required oxygen to maintain oxygen saturation (>90%), 5 weeks after onset of coronavirus disease 2019 (COVID-19) symptoms. Transbronchial lung cryobiopsy revealed pathological features of organizing pneumonia with alveolar epithelial injury, and prednisolone administration led to alleviation of respiratory symptoms and recovery of respiratory function. This case report is the first to demonstrate the use of corticosteroids to successfully treat post-COVID-19 respiratory failure in a patient with biopsy-proven organizing pneumonia. We propose that steroid treatment be considered for patients with persistent respiratory dysfunction as COVID-19 pneumonia sequelae.
Keywords: COVID-19; Cryobiopsy; Organizing pneumonia; Steroid.
. 2021 Jan 21;S2212-5345(21)00002-2.
doi: 10.1016/j.resinv.2020.12.005. Online ahead of print.
Sustained coronavirus disease 2019-related organizing pneumonia successfully treated with corticosteroid
Hiroshi Takumida[SUP] 1 [/SUP], Shinyu Izumi[SUP] 2 [/SUP], Keita Sakamoto[SUP] 2 [/SUP], Masao Hashimoto[SUP] 2 [/SUP], Satoru Ishii[SUP] 2 [/SUP], Manabu Suzuki[SUP] 2 [/SUP], Jin Takasaki[SUP] 2 [/SUP], Mariko Tanaka[SUP] 3 [/SUP], Toru Igari[SUP] 4 [/SUP], Masayuki Hojo[SUP] 2 [/SUP]
Affiliations
- PMID: 33547007
- DOI: 10.1016/j.resinv.2020.12.005
Abstract
A 70-year-old Japanese man contracted severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and required oxygen to maintain oxygen saturation (>90%), 5 weeks after onset of coronavirus disease 2019 (COVID-19) symptoms. Transbronchial lung cryobiopsy revealed pathological features of organizing pneumonia with alveolar epithelial injury, and prednisolone administration led to alleviation of respiratory symptoms and recovery of respiratory function. This case report is the first to demonstrate the use of corticosteroids to successfully treat post-COVID-19 respiratory failure in a patient with biopsy-proven organizing pneumonia. We propose that steroid treatment be considered for patients with persistent respiratory dysfunction as COVID-19 pneumonia sequelae.
Keywords: COVID-19; Cryobiopsy; Organizing pneumonia; Steroid.