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Respir Investig . Spontaneous regression of acute fibrinous organizing pneumonia induced by COVID-19 vaccination: A case report

tetano

Editor, Senior Moderator
Respir Investig


. 2024 Feb 28;62(3):356-359.
doi: 10.1016/j.resinv.2024.01.014. Online ahead of print. Spontaneous regression of acute fibrinous organizing pneumonia induced by COVID-19 vaccination: A case report

Sanshiro Haga[SUP] 1 [/SUP], Ryota Otoshi[SUP] 2 [/SUP], Akimasa Sekine[SUP] 1 [/SUP], Taichi Kaneko[SUP] 1 [/SUP], Chieri Yamada[SUP] 1 [/SUP], Tomohisa Baba[SUP] 1 [/SUP], Shigeru Komatsu[SUP] 1 [/SUP], Tomoe Sawazumi[SUP] 3 [/SUP], Tamiko Takemura[SUP] 3 [/SUP], Takashi Ogura[SUP] 1 [/SUP]



Affiliations
Abstract

A 42-year-old woman visited our hospital with complaints of fever, muscle pain, and dyspnea one week after receiving the coronavirus disease 2019 (COVID-19) vaccine. Chest high-resolution computed tomography showed a patchy consolidation and ground-glass attenuation in the both lungs, consistent with acute interstitial pneumonia. Transbronchial lung cryobiopsy revealed organizing pneumonia with marked intra-alveolar fibrin, and pathologically diagnosed as acute fibrinous organizing pneumonia (AFOP). Other causative diseases such as dermatomyositis was clinically ruled out, and COVID-19 vaccine-induced AFOP was diagnosed. Physician should check the history of COVID-19 vaccination when encountering a case of AFOP with an unknown cause.

Keywords: Acute fibrinous organizing pneumonia; COVID-19; Dermatomyositis; Transbronchial lung cryobiopsy; Vaccination.

 
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