Gert van der Hoek
In Memoriam - Editor, Senior Moderator
Resistance persists at drug-free farms
Drug-resistant germs stay in animals even if antibiotic use stops.
By Beth Marie Mole
Posted: Monday, Dec. 05, 2011
Livestock farms that stop using antibiotics may still be breeding grounds for drug-resistant germs, according to a new study. Scientists have found that bacteria in a group of Canadian pigs remained mostly impervious to two antibiotics years after farmers stopped dosing the animals. This antibiotic resistance could eventually make its way into hospitals and the human food supply, although experts caution that no link has yet been proved.
Farmers regularly treat cattle, pigs, and chickens with antibiotics to dampen low-level infections that slow the growth of these animals. But wily bacteria quickly evolve resistance. Livestock farms often brim with resistant bugs that can pass to humans and potentially spread resistance to other microbes. Scientists hypothesized that if farmers stopped using the drugs, the bacteria would lower their defenses to save energy, eventually kicking out the DNA that codes for antibiotic resistance.
To figure out if this actually happens, ecologist Martin Chenier of McGill University and his colleagues examined bacteria on a university farm that in January 2007 banned all antibiotics, including two commonly used varieties: tylosin and chlortetracycline. They monitored gut bacterial populations in 10 pigs by searching for bacteria resistant to common drugs in their waste.
To the team's surprise, the entire bug community kept most of its armor against the antibiotics, even after two years. When the researchers grew the bacteria in the lab, for example, 70 percent to 100 percent were still resistant to chlortetracycline when the pigs were slaughtered. "I didn't expect such high levels of resistance would remain," says Chenier, whose team will publish the results in the January issue of Microbial Ecology.
Read more: http://www.charlotteobserver.com/20...ance-persists-at-drug-free.html#ixzz1feTRDyJP
Drug-resistant germs stay in animals even if antibiotic use stops.
By Beth Marie Mole
Posted: Monday, Dec. 05, 2011
Livestock farms that stop using antibiotics may still be breeding grounds for drug-resistant germs, according to a new study. Scientists have found that bacteria in a group of Canadian pigs remained mostly impervious to two antibiotics years after farmers stopped dosing the animals. This antibiotic resistance could eventually make its way into hospitals and the human food supply, although experts caution that no link has yet been proved.
Farmers regularly treat cattle, pigs, and chickens with antibiotics to dampen low-level infections that slow the growth of these animals. But wily bacteria quickly evolve resistance. Livestock farms often brim with resistant bugs that can pass to humans and potentially spread resistance to other microbes. Scientists hypothesized that if farmers stopped using the drugs, the bacteria would lower their defenses to save energy, eventually kicking out the DNA that codes for antibiotic resistance.
To figure out if this actually happens, ecologist Martin Chenier of McGill University and his colleagues examined bacteria on a university farm that in January 2007 banned all antibiotics, including two commonly used varieties: tylosin and chlortetracycline. They monitored gut bacterial populations in 10 pigs by searching for bacteria resistant to common drugs in their waste.
To the team's surprise, the entire bug community kept most of its armor against the antibiotics, even after two years. When the researchers grew the bacteria in the lab, for example, 70 percent to 100 percent were still resistant to chlortetracycline when the pigs were slaughtered. "I didn't expect such high levels of resistance would remain," says Chenier, whose team will publish the results in the January issue of Microbial Ecology.
Read more: http://www.charlotteobserver.com/20...ance-persists-at-drug-free.html#ixzz1feTRDyJP