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Replication and Pathology of Duck Influenza Virus Subtype H9N2 in Chukar

tetano

Editor, Senior Moderator
Biomed Environ Sci. 2018 Apr;31(4):306-310. doi: 10.3967/bes2018.039.
[h=1]Replication and Pathology of Duck Influenza Virus Subtype H9N2 in Chukar.[/h] Zhu YC[SUP]1[/SUP], Zhang B[SUP]1[/SUP], Sun ZH[SUP]1[/SUP], Wang XJ[SUP]1[/SUP], Fan XH[SUP]1[/SUP], Gao LX[SUP]1[/SUP], Liang Y[SUP]1[/SUP], Chen XY[SUP]1[/SUP], Zhang ZF[SUP]1[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] To investigate the susceptibility of Chukars to duck avian influenza virus H9N2 and explore their role in interspecies transmission of influenza viruses. Chukars were inoculated with duck avian influenza viruses H9N2. The present study demonstrated that inflammatory lesions and virus antigen were present in the trachea, bronchus, and parabronchus, and the viruses could be isolated from throat swabs and lung tissue homogenate supernatants. At 14 d post virus inoculation, anti-H9 influenza virus antibody in the serum was detected. The results indicated that Chukars are susceptible to duck avian influenza virus and serve as an intermediate host, thereby facilitating viral gene evolution and supporting the need for continued surveillance of epidemiology and evolution of the influenza virus in Chukars.


PMID: 29773094 DOI: 10.3967/bes2018.039
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