tetano
Editor, Senior Moderator
Vaccine. 2016 May 16. pii: S0264-410X(16)30260-2. doi: 10.1016/j.vaccine.2016.04.085. [Epub ahead of print]
[h=1]Reduced serologic sensitivity to influenza A virus illness among inactivated influenza vaccinees.[/h] Thompson MG[SUP]1[/SUP], Gaglani MJ[SUP]2[/SUP], Naleway AL[SUP]3[/SUP], Dowell SH[SUP]4[/SUP], Spencer S[SUP]4[/SUP], Ball S[SUP]5[/SUP], Levine M[SUP]4[/SUP], Fry A[SUP]4[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] We compared ≥4-fold increases in antibody titers by hemagglutination inhibition assay to RT-PCR results among 42 adults with PCR-confirmed influenza A virus illnesses. Serologic sensitivity was higher among unvaccinated (69%, 95% confidence interval [CI]=48-90%) than vaccinated healthcare personnel (38%, 95% CI=29-46%) in a 2010-11 prospective cohort.
Copyright ? 2016. Published by Elsevier Ltd.
[h=4]KEYWORDS:[/h] Antibody; Hemagglutinin inhibition; Immunogenicity; Influenza; Influenza vaccine; Seroconversion; Vaccine failure
PMID: 27195761 [PubMed - as supplied by publisher]
[h=1]Reduced serologic sensitivity to influenza A virus illness among inactivated influenza vaccinees.[/h] Thompson MG[SUP]1[/SUP], Gaglani MJ[SUP]2[/SUP], Naleway AL[SUP]3[/SUP], Dowell SH[SUP]4[/SUP], Spencer S[SUP]4[/SUP], Ball S[SUP]5[/SUP], Levine M[SUP]4[/SUP], Fry A[SUP]4[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] We compared ≥4-fold increases in antibody titers by hemagglutination inhibition assay to RT-PCR results among 42 adults with PCR-confirmed influenza A virus illnesses. Serologic sensitivity was higher among unvaccinated (69%, 95% confidence interval [CI]=48-90%) than vaccinated healthcare personnel (38%, 95% CI=29-46%) in a 2010-11 prospective cohort.
Copyright ? 2016. Published by Elsevier Ltd.
[h=4]KEYWORDS:[/h] Antibody; Hemagglutinin inhibition; Immunogenicity; Influenza; Influenza vaccine; Seroconversion; Vaccine failure
PMID: 27195761 [PubMed - as supplied by publisher]