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One of the world’s largest efforts to find effective COVID-19 treatments will evaluate the impact of REGN-COV2 on mortality, hospital stays, and the need for ventilation.
14 September 2020
The University of Oxford and Regeneron Pharmaceuticals, Inc. today announced that RECOVERY (Randomised Evaluation of COVid-19 thERapY), one of the world’s largest randomised clinical trials of potential COVID-19 treatments, will evaluate Regeneron’s investigational anti-viral antibody cocktail, REGN-COV2. The Phase 3 open-label trial in patients hospitalised with COVID-19 will compare the effects of adding REGN-COV2 to the usual standard-of-care versus standard-of-care on its own.
Trial of Regeneron’s Covid-19 Antibody Drug Is Halted in Sickest Hospital Patients
Suspension is due to safety concern; testing continues in patients with less serious cases
Oct. 30, 2020 11:18 am ET
Regeneron Pharmaceuticals Inc. suspended testing of its Covid-19 antibody drug in the sickest hospitalized patients because of a safety concern, the latest setback for antibody-drug trials in patients with the most advanced disease.
Regeneron said Friday it is pausing enrollment of hospitalized Covid-19 patients receiving mechanical ventilation or high-flow oxygen, after an independent monitoring committee observed “a potential safety signal and an unfavorable risk/benefit profile at this time.”
