gsgs
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http://www.libpubmedia.co.uk/MedJ-Issues/Issue-4/Kuchipudi.htm
Avian viruses preferentially bind to sialic acid α2,3-galactose ( SAα 2,3-Gal) linked receptors,
whereas human strains bind to sialic acid α2,6-galactose ( SAα 2,6-Gal) linked receptors.
Although the intestinal epithelial cells of both species expressed only SAα 2,3-Gal receptors,
we found widespread presence of both SAα 2,6-Gal and SAα 2,3-Gal receptors in many organs
of both chickens and ducks.
In chicken trachea, SAα2,6-Gal was dominant , but in ducks it's SAα2,3-Gal.
Chicken tracheal and intestinal epithelial cells also expressed a broader range
of SAα2,3-Gal receptors (both β(1-4)GlcNAc and β(1-3)GalNAc subtypes)
in contrast to ducks, which suggests that they may be able to support infection
with a broader range of avian influenza viruses.
Avian viruses preferentially bind to sialic acid α2,3-galactose ( SAα 2,3-Gal) linked receptors,
whereas human strains bind to sialic acid α2,6-galactose ( SAα 2,6-Gal) linked receptors.
Although the intestinal epithelial cells of both species expressed only SAα 2,3-Gal receptors,
we found widespread presence of both SAα 2,6-Gal and SAα 2,3-Gal receptors in many organs
of both chickens and ducks.
In chicken trachea, SAα2,6-Gal was dominant , but in ducks it's SAα2,3-Gal.
Chicken tracheal and intestinal epithelial cells also expressed a broader range
of SAα2,3-Gal receptors (both β(1-4)GlcNAc and β(1-3)GalNAc subtypes)
in contrast to ducks, which suggests that they may be able to support infection
with a broader range of avian influenza viruses.