tetano
Editor, Senior Moderator
J Infect. 2013 Nov 21. pii: S0163-4453(13)00339-3. doi: 10.1016/j.jinf.2013.11.005. [Epub ahead of print]
Rates Of Respiratory Virus-Associated Hospitalization In Children Aged <5 Years In Rural Northern India.
Broor S, Dawood FS, Pandey BG, Saha S, Gupta V, Krishnan A, Rai S, Singh P, Erdman D, Lal RB.
Source
All India Institute of Medical Sciences, Delhi, India. Electronic address: shobha.broor@gmail.com.
Abstract
OBJECTIVES:
Though respiratory viruses are thought to cause substantial morbidity globally in children aged <5 years, the burden of severe respiratory virus infections in children is unknown in India where 20% of the world's children live.
METHODS:
During August 2009-July 2011, prospective population-based surveillance was conducted for hospitalizations of children aged <5 years in a rural community in Haryana State. Clinical data and respiratory specimens were collected. Swabs were tested by RT-PCR for influenza and parainfluenza viruses, respiratory syncytial virus (RSV), human metapneumovirus, coronaviruses, and adenovirus. Average annual hospitalization incidence was calculated using census data and adjusted for hospitalizations reported on a community healthcare utilization survey to occur at non-study hospitals.
RESULTS:
Of 245 hospitalized children, respiratory viruses were detected among 98 (40%), of whom 92 (94%) had fever or respiratory symptoms. RSV (34.6/10,000, 95% CI 26.6-44.7) accounted for the highest virus-associated hospitalization incidences and 20% of hospitalizations. There were 11.8/10,000 influenza-associated hospitalizations (7% of hospitalizations). RSV and influenza detection peaked in winter (November-February) and rainy seasons (July), respectively.
CONCLUSION:
Respiratory viruses were associated with a substantial proportion of hospitalizations among young children in a rural Indian community. Public health research and prevention in India should consider targeting RSV and influenza in young children.
? 2013 Published by Elsevier Ltd on behalf of The British Infection Association.
KEYWORDS:
Adenovirus, Coronavirus, Human Metapneumovirus, Influenza, Parainfluenza, Respiratory Syncytial Viruses, hospitalization, respiratory infections
PMID:
24269675
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/24269675
Rates Of Respiratory Virus-Associated Hospitalization In Children Aged <5 Years In Rural Northern India.
Broor S, Dawood FS, Pandey BG, Saha S, Gupta V, Krishnan A, Rai S, Singh P, Erdman D, Lal RB.
Source
All India Institute of Medical Sciences, Delhi, India. Electronic address: shobha.broor@gmail.com.
Abstract
OBJECTIVES:
Though respiratory viruses are thought to cause substantial morbidity globally in children aged <5 years, the burden of severe respiratory virus infections in children is unknown in India where 20% of the world's children live.
METHODS:
During August 2009-July 2011, prospective population-based surveillance was conducted for hospitalizations of children aged <5 years in a rural community in Haryana State. Clinical data and respiratory specimens were collected. Swabs were tested by RT-PCR for influenza and parainfluenza viruses, respiratory syncytial virus (RSV), human metapneumovirus, coronaviruses, and adenovirus. Average annual hospitalization incidence was calculated using census data and adjusted for hospitalizations reported on a community healthcare utilization survey to occur at non-study hospitals.
RESULTS:
Of 245 hospitalized children, respiratory viruses were detected among 98 (40%), of whom 92 (94%) had fever or respiratory symptoms. RSV (34.6/10,000, 95% CI 26.6-44.7) accounted for the highest virus-associated hospitalization incidences and 20% of hospitalizations. There were 11.8/10,000 influenza-associated hospitalizations (7% of hospitalizations). RSV and influenza detection peaked in winter (November-February) and rainy seasons (July), respectively.
CONCLUSION:
Respiratory viruses were associated with a substantial proportion of hospitalizations among young children in a rural Indian community. Public health research and prevention in India should consider targeting RSV and influenza in young children.
? 2013 Published by Elsevier Ltd on behalf of The British Infection Association.
KEYWORDS:
Adenovirus, Coronavirus, Human Metapneumovirus, Influenza, Parainfluenza, Respiratory Syncytial Viruses, hospitalization, respiratory infections
PMID:
24269675
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/24269675