Rare granulomatous reactions to Q fever vaccination when temporally associated to influenza vaccination

[Emily]

The primary case described here had a Q-VAX (CSL, Melbourne, Vic) vaccination followed 3 months later by Fluvax; then about 3 weeks after that the deltoid mass appeared. This type of reaction to Q-Vax is really rare, and of 5 cases that had documentation, (out of 6 total reported), 3 had temporal association with flu vaccine.

The authors suspect a causal relationship from an interaction causing immune dysfunction at the systemic, rather than local level.

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A rare granulomatous reaction
to Q fever vaccination following
influenza vaccination
Deborah Burnett and Leslie Burnett
TO THE EDITOR: We report the case of a
19-year-old female veterinary student who
presented with a 2-week history of a rapidly
growing mass on the lateral side of the del-
toid area of her left arm. On examination, the
mass was soft, freely movable, slightly warm
and non-tender...