Emily
Editor, Senior Moderator
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9116920/#
Chakrabarti SS, Tiwari A, Jaiswal S, Kaur U, Kumar I, Mittal A, Singh A, Jin K, Chakrabarti S. Rapidly Progressive Dementia with Asymmetric Rigidity Following ChAdOx1 nCoV-19 Vaccination. Aging Dis. 2022 Jun 1;13(3):633-636. doi: 10.14336/AD.2021.1102. PMID: 35656106; PMCID: PMC9116920.
Dear Editor,
A previously healthy woman in her 60s developed social isolation and behavioural abnormality in the form of moving around un-purposefully, irrelevant verbal responses and refusal to take food, one day after receiving the second dose of ChAdOx1 nCoV-19 vaccination (COVISHIELD). Her first dose (dose interval 84 days) was followed by an uneventful course and one day of mild fever. Her current condition progressed rapidly with onset of confusion, forgetfulness, and hallucinations within the next 5 days. Over the next two days, the patient developed difficulty in walking and echolalia. She was prescribed amantadine, trihexyphenidyl and clonazepam by a local practitioner but she showed further deterioration in the form of irritability, incoherent speech, aggravated forgetfulness, auditory and visual hallucinations, abnormal movements of limbs, and jaw and neck dystonia...
..
Chakrabarti SS, Tiwari A, Jaiswal S, Kaur U, Kumar I, Mittal A, Singh A, Jin K, Chakrabarti S. Rapidly Progressive Dementia with Asymmetric Rigidity Following ChAdOx1 nCoV-19 Vaccination. Aging Dis. 2022 Jun 1;13(3):633-636. doi: 10.14336/AD.2021.1102. PMID: 35656106; PMCID: PMC9116920.
Dear Editor,
A previously healthy woman in her 60s developed social isolation and behavioural abnormality in the form of moving around un-purposefully, irrelevant verbal responses and refusal to take food, one day after receiving the second dose of ChAdOx1 nCoV-19 vaccination (COVISHIELD). Her first dose (dose interval 84 days) was followed by an uneventful course and one day of mild fever. Her current condition progressed rapidly with onset of confusion, forgetfulness, and hallucinations within the next 5 days. Over the next two days, the patient developed difficulty in walking and echolalia. She was prescribed amantadine, trihexyphenidyl and clonazepam by a local practitioner but she showed further deterioration in the form of irritability, incoherent speech, aggravated forgetfulness, auditory and visual hallucinations, abnormal movements of limbs, and jaw and neck dystonia...
..