tetano
Editor, Senior Moderator
Radiol Infect Dis
. 2020 Aug 8.
doi: 10.1016/j.jrid.2020.07.007. Online ahead of print.
Changes in CT manifestations and RT-PCR testings of the coronavirus disease 2019 until recovery in patients with afferent infection vs. second-generation infection outside the original city (Wuhan): An observational study
Sun Tang[SUP] 1 [/SUP], Jing Ou[SUP] 1 [/SUP], Rui Li[SUP] 1 [/SUP], Xiao-Ming Zhang[SUP] 1 [/SUP], Tian-Wu Chen[SUP] 1 [/SUP], Hong-Jun Li[SUP] 2 [/SUP]
Affiliations
Abstract
Objective: To investigate changes in CT manifestations and results of reverse transcription polymerase chain reaction (RT-PCR) testing between afferent and second-generation coronavirus disease 2019 (COVID-19) outside the original city (Wuhan) until recovery.
Methods: We collected 26 consecutive COVID-19 patients undergoing initial and follow-up CT scans together with RT-PCR until recovery from 2 hospitals outside the original city. Seventeen patients with afferent infection and 9 with second-generation infection were assigned to Group A and B, respectively. By observing CT manifestations, we scored COVID-19, and statistically analyzed numbers of patients with changes in CT scores and RT-PCR results between stages.
Results: The total score of COVID-19 on initial CT manifestations was higher in Group A than in Group B (P < 0.05). COVID-19 progressed more frequently from stage 1-2, and relieved from stage 3-4 in Group A (P < 0.05). The similar trend in Group A could not be found in Group B. Results of RT-PCR in most of patients in Group A turned negative at stage 4 while those in Group B turned negative at stage 3 (P < 0.05).
Conclusion: Changes in CT manifestation and RT-PCR result can be different between afferent and second-generation COVID-19 until recovery.
Keywords: Computed tomography; Coronavirus; Infection; Pneumonia; Polymerase chain reaction.
. 2020 Aug 8.
doi: 10.1016/j.jrid.2020.07.007. Online ahead of print.
Changes in CT manifestations and RT-PCR testings of the coronavirus disease 2019 until recovery in patients with afferent infection vs. second-generation infection outside the original city (Wuhan): An observational study
Sun Tang[SUP] 1 [/SUP], Jing Ou[SUP] 1 [/SUP], Rui Li[SUP] 1 [/SUP], Xiao-Ming Zhang[SUP] 1 [/SUP], Tian-Wu Chen[SUP] 1 [/SUP], Hong-Jun Li[SUP] 2 [/SUP]
Affiliations
- PMID: 32838010
- PMCID: PMC7414381
- DOI: 10.1016/j.jrid.2020.07.007
Abstract
Objective: To investigate changes in CT manifestations and results of reverse transcription polymerase chain reaction (RT-PCR) testing between afferent and second-generation coronavirus disease 2019 (COVID-19) outside the original city (Wuhan) until recovery.
Methods: We collected 26 consecutive COVID-19 patients undergoing initial and follow-up CT scans together with RT-PCR until recovery from 2 hospitals outside the original city. Seventeen patients with afferent infection and 9 with second-generation infection were assigned to Group A and B, respectively. By observing CT manifestations, we scored COVID-19, and statistically analyzed numbers of patients with changes in CT scores and RT-PCR results between stages.
Results: The total score of COVID-19 on initial CT manifestations was higher in Group A than in Group B (P < 0.05). COVID-19 progressed more frequently from stage 1-2, and relieved from stage 3-4 in Group A (P < 0.05). The similar trend in Group A could not be found in Group B. Results of RT-PCR in most of patients in Group A turned negative at stage 4 while those in Group B turned negative at stage 3 (P < 0.05).
Conclusion: Changes in CT manifestation and RT-PCR result can be different between afferent and second-generation COVID-19 until recovery.
Keywords: Computed tomography; Coronavirus; Infection; Pneumonia; Polymerase chain reaction.