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Radiol Case Rep . A case of influenza-associated invasive aspergillosis with cerebral hemorrhage due to infectious vasculopathy

tetano

Editor, Senior Moderator
Radiol Case Rep


. 2021 Nov 26;17(2):326-331.
doi: 10.1016/j.radcr.2021.10.031. eCollection 2022 Feb.
A case of influenza-associated invasive aspergillosis with cerebral hemorrhage due to infectious vasculopathy


Ryou Izumiya[SUP] 1 [/SUP], Yasuhiko Fujita[SUP] 1 [/SUP], Teruyoshi Amagai[SUP] 1 2 [/SUP]



Affiliations
Free PMC article

Abstract

An invasive aspergillosis (IA) primarily occurs among immunocompromised patients. Recently with an influenzae infection prevalently spreading, influenzae-associated invasive aspergillosis (IAIA) has been reported occasionally. By contrast, neuroleptic malignant syndrome (NMS) occurs rarely in psychiatric patients who are treated with Olanzapine. We report a 43 years old male with psychiatric disorder who had developed IAIA followed by NMS and cerebral hemorrhage as the result of aspergillus invasion to cerebral vessels. He had also super-infection of COVID-19, 13 months later to be saved completely after invasive mechanical respiratory supports. From clinical aspects, we would emphasize that it is of importance to find earlier co-occurrence of IAIA patients with cerebral hemorrhage due to secondary infectious vasculopathy of IA.

Keywords: COVID-19; Cerebral hemorrhage; Co-infection; Infectious vasculopathy; Influenza-associated IA; Invasive aspergillosis (IA); Neuroleptic malignant syndrome; Super-infection.
 
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