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The concern over the movement of the Qingahi strains to vast regions is pretty obvious. I have posted numerous examples of acquired changes including receptor binding domain changes in clade 2.2 (Qinghai) in Turkey, Iraq, Azerbaijan, and Egypt. Asssociated with those changes have been human cases in Turkey, Iraq, Azerbaijan, Egypt, Djibouti, Nigeria, and Pakistan (and almost certainly in unreported cases in India and Bangladesh). None of the above locations had reported H5N1 prior to the migratory bird expansion beginning in the spring of 2005. The Paksitan transmission is the most sustained to date, and virtually all of the Qinghai isolates have PB2 E627K, which is linked to increased replication at mammalian body temperatures.are there transcripts ? That's easier to read, you can scip passages and I
don't understand English so well when the noise quality is bad and people
talk quickly.
OK, I listened to the niman-talk.
I think he didn't make clear why the spread to Russia,Europe,Africa
was so dangerous.
I mean, if H5N1 wants to go pandemic, it could do so just in China ?!
However we have HIV in Africa, many poor countries,India,Bangladesh,Africa,
who may not be capable to contain the bird-situation by measures as in Hongkong,
China,Vietnam,Thailand.
We have different genotypes in local bird's influenza to reassort with,
different conditions to adapt, weather, host species.
Much more opprtunities for the virus.
Well,... I still think China is most dangerous, though.
Just because of the large diversity, the many reassortments there.
Awesome, Florida1! And, Dr. Niman, too. Look forward to listening to the podcasts.
:applause: :applause: :applause:
"Magnana"Ok Florida! How'd it go? And when can the rest of us get transcripts? :applause: