tetano
Editor, Senior Moderator
Public Health
. 2021 May 9;195:132-134.
doi: 10.1016/j.puhe.2021.04.027. Online ahead of print.
SARS-CoV-2 contact tracing among disadvantaged populations during epidemic intervals should be a priority strategy: results from a pilot experiment in Barcelona
X Vallès[SUP] 1 [/SUP], S Roure[SUP] 2 [/SUP], L Valerio[SUP] 3 [/SUP], I López-Muñoz[SUP] 3 [/SUP], O Pérez-Quílez[SUP] 3 [/SUP], L Soldevila[SUP] 2 [/SUP], L Martín-Cano[SUP] 3 [/SUP], O Estrada[SUP] 4 [/SUP], M D Palacín[SUP] 3 [/SUP], I Blanco[SUP] 5 [/SUP], J Orozco[SUP] 6 [/SUP], A Esquerrà[SUP] 7 [/SUP], X Villanova[SUP] 3 [/SUP]
Affiliations
Abstract
Objectives: The aim of this study was to trace contacts of coronavirus disease 2019 (COVID-19) hospitalised patients and determine the risk factors of infection in urban areas.
Study design: Longitudinal analysis of contacts identified from index cases.
Methods: A contact tracing study was carried out in the Northern Metropolitan area of Barcelona, Spain, during the inter-epidemic lapse of May to July 2020, a period of low SARS-CoV-2 incidence. Index cases were notified from the referral hospital. Contacts were traced and followed up for 14 days. Reverse transcription polymerase chain reaction was performed on day 0 and day 14 for contacts.
Results: In total, 368 contacts were identified from 81 index cases (median of seven contacts per index case), from which 308 were traced successfully. The median age of contacts was 28 years, 62% (223 of 368) were men. During the follow-up period, 100 contacts tested positive for COVID-19 (32.5% [95% confidence interval {CI} = 27.3-38.0]), with a secondary infection rate of 48.3% (95% CI = 40.8-55.9) among housemates. Clusters of index and respective contacts tended to aggregate within disadvantaged neighbourhoods (P < 0.001), and non-national index cases (N = 28, 34.1%) resulted in higher secondary infection rates compared with nationals (51.0% [95% CI = 41.0-60.9] vs 22.3% [95% CI = 16.8-28.8]; P < 0.001).
Conclusions: Disadvantaged communities experience a disproportionate burden of COVID-19 and may act as infection reservoirs. Contact tracing with a cross-cutting approach among these communities is required, especially during inter-epidemic periods.
Keywords: COVID-19; Contact tracing; SARS-CoV-2; Social determinants.
. 2021 May 9;195:132-134.
doi: 10.1016/j.puhe.2021.04.027. Online ahead of print.
SARS-CoV-2 contact tracing among disadvantaged populations during epidemic intervals should be a priority strategy: results from a pilot experiment in Barcelona
X Vallès[SUP] 1 [/SUP], S Roure[SUP] 2 [/SUP], L Valerio[SUP] 3 [/SUP], I López-Muñoz[SUP] 3 [/SUP], O Pérez-Quílez[SUP] 3 [/SUP], L Soldevila[SUP] 2 [/SUP], L Martín-Cano[SUP] 3 [/SUP], O Estrada[SUP] 4 [/SUP], M D Palacín[SUP] 3 [/SUP], I Blanco[SUP] 5 [/SUP], J Orozco[SUP] 6 [/SUP], A Esquerrà[SUP] 7 [/SUP], X Villanova[SUP] 3 [/SUP]
Affiliations
- PMID: 34111802
- PMCID: PMC8106905
- DOI: 10.1016/j.puhe.2021.04.027
Abstract
Objectives: The aim of this study was to trace contacts of coronavirus disease 2019 (COVID-19) hospitalised patients and determine the risk factors of infection in urban areas.
Study design: Longitudinal analysis of contacts identified from index cases.
Methods: A contact tracing study was carried out in the Northern Metropolitan area of Barcelona, Spain, during the inter-epidemic lapse of May to July 2020, a period of low SARS-CoV-2 incidence. Index cases were notified from the referral hospital. Contacts were traced and followed up for 14 days. Reverse transcription polymerase chain reaction was performed on day 0 and day 14 for contacts.
Results: In total, 368 contacts were identified from 81 index cases (median of seven contacts per index case), from which 308 were traced successfully. The median age of contacts was 28 years, 62% (223 of 368) were men. During the follow-up period, 100 contacts tested positive for COVID-19 (32.5% [95% confidence interval {CI} = 27.3-38.0]), with a secondary infection rate of 48.3% (95% CI = 40.8-55.9) among housemates. Clusters of index and respective contacts tended to aggregate within disadvantaged neighbourhoods (P < 0.001), and non-national index cases (N = 28, 34.1%) resulted in higher secondary infection rates compared with nationals (51.0% [95% CI = 41.0-60.9] vs 22.3% [95% CI = 16.8-28.8]; P < 0.001).
Conclusions: Disadvantaged communities experience a disproportionate burden of COVID-19 and may act as infection reservoirs. Contact tracing with a cross-cutting approach among these communities is required, especially during inter-epidemic periods.
Keywords: COVID-19; Contact tracing; SARS-CoV-2; Social determinants.