tetano
Editor, Senior Moderator
Public Health
. 2020 Oct 23;189:153-157.
doi: 10.1016/j.puhe.2020.10.012. Online ahead of print.
Predictors of laboratory-positive COVID-19 in children and teenagers
E Murillo-Zamora[SUP] 1 [/SUP], F Aguilar-Sollano[SUP] 2 [/SUP], I Delgado-Enciso[SUP] 3 [/SUP], C M Hernandez-Suarez[SUP] 4 [/SUP]
Affiliations
Abstract
Objective: The aim of the study was to identify factors predicting laboratory-positive coronavirus disease 2019 (COVID-19) in pediatric patients with acute respiratory symptoms.
Study design: We conducted a cross-sectional analysis of a prospective cohort study.
Methods: Data from 1849 individuals were analyzed. COVID-19 was confirmed (reverse transcription-quantitative polymerase chain reaction) in 15.9% of patients, and factors predicting a positive test result were evaluated through prevalence odds ratios and 95% confidence intervals.
Results: Increasing age, personal history of obesity, and household contact with a case were found to be associated, in the multiple regression model, with increased odds of a positive test result. Young patients residing in areas with higher population sizes, as well as those with severe respiratory symptoms, were less likely to be laboratory confirmed.
Conclusions: Early identification and isolation of children and teenagers with suggestive symptoms of COVID-19 is important to limit viral spread. We identified several factors predicting the laboratory test result. Our findings are relevant from a public health policy perspective, particularly after the restart of in-person academic activities.
Keywords: Adolescent; COVID-19; Child; Odds ratio; Real-time polymerase chain reaction.
. 2020 Oct 23;189:153-157.
doi: 10.1016/j.puhe.2020.10.012. Online ahead of print.
Predictors of laboratory-positive COVID-19 in children and teenagers
E Murillo-Zamora[SUP] 1 [/SUP], F Aguilar-Sollano[SUP] 2 [/SUP], I Delgado-Enciso[SUP] 3 [/SUP], C M Hernandez-Suarez[SUP] 4 [/SUP]
Affiliations
- PMID: 33246302
- PMCID: PMC7584439
- DOI: 10.1016/j.puhe.2020.10.012
Abstract
Objective: The aim of the study was to identify factors predicting laboratory-positive coronavirus disease 2019 (COVID-19) in pediatric patients with acute respiratory symptoms.
Study design: We conducted a cross-sectional analysis of a prospective cohort study.
Methods: Data from 1849 individuals were analyzed. COVID-19 was confirmed (reverse transcription-quantitative polymerase chain reaction) in 15.9% of patients, and factors predicting a positive test result were evaluated through prevalence odds ratios and 95% confidence intervals.
Results: Increasing age, personal history of obesity, and household contact with a case were found to be associated, in the multiple regression model, with increased odds of a positive test result. Young patients residing in areas with higher population sizes, as well as those with severe respiratory symptoms, were less likely to be laboratory confirmed.
Conclusions: Early identification and isolation of children and teenagers with suggestive symptoms of COVID-19 is important to limit viral spread. We identified several factors predicting the laboratory test result. Our findings are relevant from a public health policy perspective, particularly after the restart of in-person academic activities.
Keywords: Adolescent; COVID-19; Child; Odds ratio; Real-time polymerase chain reaction.