tetano
Editor, Senior Moderator
Med Mal Infect. 2017 Dec 16. pii: S0399-077X(16)30838-1. doi: 10.1016/j.medmal.2017.11.007. [Epub ahead of print]
[h=1]Prospective comparative study of characteristics associated with influenza A and B in adults.[/h] Chagvardieff A[SUP]1[/SUP], Persico N[SUP]2[/SUP], Marmillot C[SUP]2[/SUP], Badiaga S[SUP]3[/SUP], Charrel R[SUP]4[/SUP], Roch A[SUP]5[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]OBJECTIVES:[/h] To describe and compare the epidemiological characteristics associated with influenza type A and B as well as the characteristics associated with influenza pneumonia. The secondary objective was to evaluate the performance of influenza rapid diagnostic tests (RDT) in the emergency department.
[h=4]PATIENTS AND METHODS:[/h] Prospective study, including 251 adult patients admitted to the emergency department during the 2013-2014 influenza outbreaks for flu-like illness confirmed by RT-PCR.
[h=4]RESULTS:[/h] A total of 106 patients were infected with influenza type B (42%) and 145 with influenza type A (58%). Mean age was 56 and the sex-ratio was 0.9. In a multivariate analysis, the only factor independently related with the type of influenza strain was the patient's age. Overall, 17% of influenza-infected patients were vaccinated and 38% presented with pneumonia, with no significant difference between strains. In a univariate analysis, the risk factors associated with the occurrence of pneumonia were age, vaccination, and chronic obstructive pulmonary disease. Only 22% of samples positive by RT-PCR for influenza B and 40% for influenza A were positive by RDT.
[h=4]CONCLUSION:[/h] Influenza type A and type B had similar clinical and biological signs, including severity. Influenza type B should not be neglected. Any emergency department may use the RDT for its ease-of-use and rapidity. However, its low sensitivity should be taken into consideration when interpreting results.
Copyright ? 2017 Elsevier Masson SAS. All rights reserved.
[h=4]KEYWORDS:[/h] Epidemiology; Grippe; Influenza; Pneumonia; Pneumonie; Rapid diagnostic test; Test de diagnostic rapide; ?pid?miologie
PMID: 29258804 DOI: 10.1016/j.medmal.2017.11.007
[h=1]Prospective comparative study of characteristics associated with influenza A and B in adults.[/h] Chagvardieff A[SUP]1[/SUP], Persico N[SUP]2[/SUP], Marmillot C[SUP]2[/SUP], Badiaga S[SUP]3[/SUP], Charrel R[SUP]4[/SUP], Roch A[SUP]5[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]OBJECTIVES:[/h] To describe and compare the epidemiological characteristics associated with influenza type A and B as well as the characteristics associated with influenza pneumonia. The secondary objective was to evaluate the performance of influenza rapid diagnostic tests (RDT) in the emergency department.
[h=4]PATIENTS AND METHODS:[/h] Prospective study, including 251 adult patients admitted to the emergency department during the 2013-2014 influenza outbreaks for flu-like illness confirmed by RT-PCR.
[h=4]RESULTS:[/h] A total of 106 patients were infected with influenza type B (42%) and 145 with influenza type A (58%). Mean age was 56 and the sex-ratio was 0.9. In a multivariate analysis, the only factor independently related with the type of influenza strain was the patient's age. Overall, 17% of influenza-infected patients were vaccinated and 38% presented with pneumonia, with no significant difference between strains. In a univariate analysis, the risk factors associated with the occurrence of pneumonia were age, vaccination, and chronic obstructive pulmonary disease. Only 22% of samples positive by RT-PCR for influenza B and 40% for influenza A were positive by RDT.
[h=4]CONCLUSION:[/h] Influenza type A and type B had similar clinical and biological signs, including severity. Influenza type B should not be neglected. Any emergency department may use the RDT for its ease-of-use and rapidity. However, its low sensitivity should be taken into consideration when interpreting results.
Copyright ? 2017 Elsevier Masson SAS. All rights reserved.
[h=4]KEYWORDS:[/h] Epidemiology; Grippe; Influenza; Pneumonia; Pneumonie; Rapid diagnostic test; Test de diagnostic rapide; ?pid?miologie
PMID: 29258804 DOI: 10.1016/j.medmal.2017.11.007