tetano
Editor, Senior Moderator
Proc Biol Sci
. 2021 Apr 28;288(1949):20203074.
doi: 10.1098/rspb.2020.3074. Epub 2021 Apr 28.
Five approaches to the suppression of SARS-CoV-2 without intensive social distancing
John M Drake[SUP] 1 2 [/SUP], Kyle Dahlin[SUP] 1 2 [/SUP], Pejman Rohani[SUP] 1 2 [/SUP], Andreas Handel[SUP] 2 3 [/SUP]
Affiliations
Abstract
Initial efforts to mitigate transmission of SARS-CoV-2 relied on intensive social distancing measures such as school and workplace closures, shelter-in-place orders and prohibitions on the gathering of people. Other non-pharmaceutical interventions for suppressing transmission include active case finding, contact tracing, quarantine, immunity or health certification, and a wide range of personal protective measures. Here we investigate the potential effectiveness of these alternative approaches to suppression. We introduce a conceptual framework represented by two mathematical models that differ in strategy. We find both strategies may be effective, although both require extensive testing and work within a relatively narrow range of conditions. Generalized protective measures such as wearing face masks, improved hygiene and local reductions in density are found to significantly increase the effectiveness of targeted interventions.
Keywords: COVID-19; SARS-CoV-2; coronavirus; non-pharmaceutical interventions.
. 2021 Apr 28;288(1949):20203074.
doi: 10.1098/rspb.2020.3074. Epub 2021 Apr 28.
Five approaches to the suppression of SARS-CoV-2 without intensive social distancing
John M Drake[SUP] 1 2 [/SUP], Kyle Dahlin[SUP] 1 2 [/SUP], Pejman Rohani[SUP] 1 2 [/SUP], Andreas Handel[SUP] 2 3 [/SUP]
Affiliations
- PMID: 33906405
- DOI: 10.1098/rspb.2020.3074
Abstract
Initial efforts to mitigate transmission of SARS-CoV-2 relied on intensive social distancing measures such as school and workplace closures, shelter-in-place orders and prohibitions on the gathering of people. Other non-pharmaceutical interventions for suppressing transmission include active case finding, contact tracing, quarantine, immunity or health certification, and a wide range of personal protective measures. Here we investigate the potential effectiveness of these alternative approaches to suppression. We introduce a conceptual framework represented by two mathematical models that differ in strategy. We find both strategies may be effective, although both require extensive testing and work within a relatively narrow range of conditions. Generalized protective measures such as wearing face masks, improved hygiene and local reductions in density are found to significantly increase the effectiveness of targeted interventions.
Keywords: COVID-19; SARS-CoV-2; coronavirus; non-pharmaceutical interventions.