Ronan Kelly
Retired 2020
Case Reports in Medicine
Volume 2012 (2012), Article ID 782854, 4 pages
doi:10.1155/2012/782854
Case Report
Primary Amoebic Meningoencephalitis in an Iranian Infant
Zahra Movahedi,1 Mohammad Reza Shokrollahi,1 Mohammad Aghaali,1 and Hosein Heydari1,2
1Qom University of Medical Science, Qom, Iran
2Department of Prdiatric Infectious Disease, Qom Children Hospital, Qom University of Medical Science, Imam Boulevard, Qom 37185-3458, Iran
Received 10 April 2012; Revised 20 June 2012; Accepted 20 June 2012
Academic Editor: Arduino A. Mangoni
Copyright ? 2012 Zahra Movahedi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Introduction. Naegleria fowleri, a free living amoeba, can cause devastating and deadly diseases in humans. This is the first report of primary amoebic meningoencephalitis from Iran. Case report. A five-month-old male infant presented with the history of fever and eye gaze for three days, after beginning of bacterial meningitis, a plain and contrast CT revealed communicated hydrocephalus. In the repeat of CSF analysis on microscopic examination of wet preparation of CSF, Naegleria Fowleri was seen. Then, Amphotericin B and Rifampin were started. On followup, two months later, the patient was totally asymptomatic. Conclusion. Though occurrence of PAM is rare, this unusual disease has grave prognosis, so infection with free living amoebas must be considered in differential diagnosis of pediatric patients of purulent meningitis without evidence of bacteria on Gram?s stain and imaging findings, nonspecific brain edema on CT or hydrocephalus even without history of contact.
...
Full Paper at; http://www.hindawi.com/journals/crim/2012/782854/
Volume 2012 (2012), Article ID 782854, 4 pages
doi:10.1155/2012/782854
Case Report
Primary Amoebic Meningoencephalitis in an Iranian Infant
Zahra Movahedi,1 Mohammad Reza Shokrollahi,1 Mohammad Aghaali,1 and Hosein Heydari1,2
1Qom University of Medical Science, Qom, Iran
2Department of Prdiatric Infectious Disease, Qom Children Hospital, Qom University of Medical Science, Imam Boulevard, Qom 37185-3458, Iran
Received 10 April 2012; Revised 20 June 2012; Accepted 20 June 2012
Academic Editor: Arduino A. Mangoni
Copyright ? 2012 Zahra Movahedi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Introduction. Naegleria fowleri, a free living amoeba, can cause devastating and deadly diseases in humans. This is the first report of primary amoebic meningoencephalitis from Iran. Case report. A five-month-old male infant presented with the history of fever and eye gaze for three days, after beginning of bacterial meningitis, a plain and contrast CT revealed communicated hydrocephalus. In the repeat of CSF analysis on microscopic examination of wet preparation of CSF, Naegleria Fowleri was seen. Then, Amphotericin B and Rifampin were started. On followup, two months later, the patient was totally asymptomatic. Conclusion. Though occurrence of PAM is rare, this unusual disease has grave prognosis, so infection with free living amoebas must be considered in differential diagnosis of pediatric patients of purulent meningitis without evidence of bacteria on Gram?s stain and imaging findings, nonspecific brain edema on CT or hydrocephalus even without history of contact.
...
Full Paper at; http://www.hindawi.com/journals/crim/2012/782854/