tetano
Editor, Senior Moderator
Oncoimmunology. 2013 Nov 1;2(11):e26618. Epub 2013 Oct 10.
Preventing surgery-induced NK cell dysfunction and cancer metastases with influenza vaccination.
Tai LH1, Zhang J2, Auer RC3.
Author information
Abstract
Surgical resection is the mainstay of treatment for solid tumors, but the postoperative period is uniquely inclined to the formation of metastases, largely due to the suppression of natural killer (NK) cells. We found that preoperative influenza vaccination prevents postoperative NK-cell dysfunction, attenuating tumor dissemination in murine models and promoting the activation of NK cells in cancer patients.
KEYWORDS:
cancer metastases, immunosuppression, influenza vaccine, natural killer cells, surgical stress
PMID:
24404430
[PubMed]
http://www.ncbi.nlm.nih.gov/pubmed/24404430
Preventing surgery-induced NK cell dysfunction and cancer metastases with influenza vaccination.
Tai LH1, Zhang J2, Auer RC3.
Author information
Abstract
Surgical resection is the mainstay of treatment for solid tumors, but the postoperative period is uniquely inclined to the formation of metastases, largely due to the suppression of natural killer (NK) cells. We found that preoperative influenza vaccination prevents postoperative NK-cell dysfunction, attenuating tumor dissemination in murine models and promoting the activation of NK cells in cancer patients.
KEYWORDS:
cancer metastases, immunosuppression, influenza vaccine, natural killer cells, surgical stress
PMID:
24404430
[PubMed]
http://www.ncbi.nlm.nih.gov/pubmed/24404430