tetano
Editor, Senior Moderator
Enferm Infecc Microbiol Clin. 2017 Nov 24. pii: S0213-005X(17)30321-X. doi: 10.1016/j.eimc.2017.10.021. [Epub ahead of print]
[h=1]Prevalence of antibodies and humoral response after seasonal trivalent vaccination against influenza B lineages in an elderly population of Spain.[/h] [Article in English, Spanish]
Mu?oz IS[SUP]1[/SUP], Rello SR[SUP]2[/SUP], Lejarazu RO[SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]INTRODUCTION:[/h] The aim of this study was to analyze the presence of antibodies against both Yamagata and Victoria influenza B lineages and to check the response after seasonal trivalent vaccination.
[h=4]MATERIALS AND METHODS:[/h] Haemagglutination inhibition assays were performed with pre-and post-vaccination serum samples from 174 individuals ≥65 years of age vaccinated with seasonal trivalent influenza vaccines during the 2006-2007, 2008-2009, 2009-2010 and 2010-2011 vaccine campaigns.
[h=4]RESULTS:[/h] 33.9% of individuals showed pre-vaccine protective antibodies (≥1/40) against B/Yamagata lineage and 41.4% against B/Victoria lineage. The annual trivalent vaccine induced significant homologous seroconversion in 14-35.6% of individuals in each vaccine campaign.
[h=4]CONCLUSIONS:[/h] The population ≥65 years has low-moderate seroprotection against B influenza lineages. Trivalent vaccination induced a slight increase of seroprotection. The trivalent vaccine should be administered to all individuals ≥65 years in all vaccine campaigns.
Copyright ? 2017 Elsevier Espa?a, S.L.U. and Sociedad Espa?ola de Enfermedades Infecciosas y Microbiolog?a Cl?nica. All rights reserved.
[h=4]KEYWORDS:[/h] Antibodies; Anticuerpos; Influenza B lineages; Linajes de gripe B; Trivalent influenza vaccination; Vacuna trivalente de gripe
PMID: 29179984 DOI: 10.1016/j.eimc.2017.10.021
[h=1]Prevalence of antibodies and humoral response after seasonal trivalent vaccination against influenza B lineages in an elderly population of Spain.[/h] [Article in English, Spanish]
Mu?oz IS[SUP]1[/SUP], Rello SR[SUP]2[/SUP], Lejarazu RO[SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]INTRODUCTION:[/h] The aim of this study was to analyze the presence of antibodies against both Yamagata and Victoria influenza B lineages and to check the response after seasonal trivalent vaccination.
[h=4]MATERIALS AND METHODS:[/h] Haemagglutination inhibition assays were performed with pre-and post-vaccination serum samples from 174 individuals ≥65 years of age vaccinated with seasonal trivalent influenza vaccines during the 2006-2007, 2008-2009, 2009-2010 and 2010-2011 vaccine campaigns.
[h=4]RESULTS:[/h] 33.9% of individuals showed pre-vaccine protective antibodies (≥1/40) against B/Yamagata lineage and 41.4% against B/Victoria lineage. The annual trivalent vaccine induced significant homologous seroconversion in 14-35.6% of individuals in each vaccine campaign.
[h=4]CONCLUSIONS:[/h] The population ≥65 years has low-moderate seroprotection against B influenza lineages. Trivalent vaccination induced a slight increase of seroprotection. The trivalent vaccine should be administered to all individuals ≥65 years in all vaccine campaigns.
Copyright ? 2017 Elsevier Espa?a, S.L.U. and Sociedad Espa?ola de Enfermedades Infecciosas y Microbiolog?a Cl?nica. All rights reserved.
[h=4]KEYWORDS:[/h] Antibodies; Anticuerpos; Influenza B lineages; Linajes de gripe B; Trivalent influenza vaccination; Vacuna trivalente de gripe
PMID: 29179984 DOI: 10.1016/j.eimc.2017.10.021