tetano
Editor, Senior Moderator
Int J Health Sci (Qassim). 2019 Jul-Aug;13(4):56-62.
[h=1]Prevalence and mortality due to acute kidney injuries in patients with influenza A (H1N1) viral infection: A systemic narrative review.[/h] Dalbhi SA[SUP]1[/SUP], Alshahrani HA[SUP]2[/SUP], Almadi A[SUP]3[/SUP], Busaleh H[SUP]4[/SUP], Alotaibi M[SUP]5[/SUP], Almutairi W[SUP]6[/SUP], Almukhrq Z[SUP]7[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]Introduction:[/h] There is limited evidence of studying the associated factors of acute kidney injury (AKI) among patients with influenza A (H1N1) virus infection pandemic in 2009. AKI is one of the most prevalent complications in the intensive care unit. Its incidence is associated with high mortality and negative impacts on long-term survival. The aim of this narrative review was to determine the prevalence and mortality due to AKI, among patients admitted with the H1N1 virus.
[h=4]Materials and Methods:[/h] A narrative review of studies reporting about treatment measures and mortality associated with AKI during the H1N1 pandemic over a 10-year period (from September 2009 to August 2018), was performed. We searched the following databases; EMBASE, Medline/PubMed, NHS evidence, Google Scholar, and the Cochrane Library. Our inclusion revealed 20 studies of patients (n = 3579) who were admitted with H1N1 infection and developed AKI.
[h=4]Results:[/h] In this study, 33% of patients (n = 1164) who were admitted with H1N1 infection had developed AKI. Within the first 5 years (2009 to 2013), 36% of patients (n = 1013) developed AKI. Within the next 5 years (2014-2018), 812 patients were admitted with the H1N1 infection and 18% of patients (n = 150) had developed AKI. Over the 10 years, there was a 50% reduction in the number of patients who developed AKI (2009 and 2018) (P < 0.0001).
[h=4]Conclusion:[/h] Patients showed varied responses to treatment measures, depending on their geographical location, comorbidities, and other characteristics. Despite a reasonable prevalence of AKI among patients with the H1N1 virus infection, the mortality over the last 10 years was reduced, with renal replacement therapy as a common therapy in most studies.
[h=4]KEYWORDS:[/h] Acute kidney injury; influenza A; mortality; review; treatment measures
PMID: 31341456
[h=1]Prevalence and mortality due to acute kidney injuries in patients with influenza A (H1N1) viral infection: A systemic narrative review.[/h] Dalbhi SA[SUP]1[/SUP], Alshahrani HA[SUP]2[/SUP], Almadi A[SUP]3[/SUP], Busaleh H[SUP]4[/SUP], Alotaibi M[SUP]5[/SUP], Almutairi W[SUP]6[/SUP], Almukhrq Z[SUP]7[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]Introduction:[/h] There is limited evidence of studying the associated factors of acute kidney injury (AKI) among patients with influenza A (H1N1) virus infection pandemic in 2009. AKI is one of the most prevalent complications in the intensive care unit. Its incidence is associated with high mortality and negative impacts on long-term survival. The aim of this narrative review was to determine the prevalence and mortality due to AKI, among patients admitted with the H1N1 virus.
[h=4]Materials and Methods:[/h] A narrative review of studies reporting about treatment measures and mortality associated with AKI during the H1N1 pandemic over a 10-year period (from September 2009 to August 2018), was performed. We searched the following databases; EMBASE, Medline/PubMed, NHS evidence, Google Scholar, and the Cochrane Library. Our inclusion revealed 20 studies of patients (n = 3579) who were admitted with H1N1 infection and developed AKI.
[h=4]Results:[/h] In this study, 33% of patients (n = 1164) who were admitted with H1N1 infection had developed AKI. Within the first 5 years (2009 to 2013), 36% of patients (n = 1013) developed AKI. Within the next 5 years (2014-2018), 812 patients were admitted with the H1N1 infection and 18% of patients (n = 150) had developed AKI. Over the 10 years, there was a 50% reduction in the number of patients who developed AKI (2009 and 2018) (P < 0.0001).
[h=4]Conclusion:[/h] Patients showed varied responses to treatment measures, depending on their geographical location, comorbidities, and other characteristics. Despite a reasonable prevalence of AKI among patients with the H1N1 virus infection, the mortality over the last 10 years was reduced, with renal replacement therapy as a common therapy in most studies.
[h=4]KEYWORDS:[/h] Acute kidney injury; influenza A; mortality; review; treatment measures
PMID: 31341456