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Preprint: Emergence in late 2020 of multiple lineages of SARS-CoV-2 Spike protein variants affecting amino acid position 677

Missouriwatcher

Editor, Senior Moderator
Medrxiv
Emergence in late 2020 of multiple lineages of SARS-CoV-2 Spike protein variants affecting amino acid position 677

View ORCID ProfileEmma B Hodcroft, View ORCID ProfileDaryl B Domman, Daniel J Snyder, View ORCID ProfileKasopefoluwa Oguntuyo, View ORCID ProfileMaarten Van Diest, Kenneth H Densmore, Kurt C Schwalm, Jon Femling, Jennifer L Carroll, Rona S Scott, Martha M Whyte, Michael D Edwards, View ORCID ProfileNoah C Hull, View ORCID ProfileChristopher G Kevil, John A Vanchiere, Benhur Lee, View ORCID ProfileDarrell L Dinwiddie, View ORCID ProfileVaughn S Cooper, View ORCID ProfileJeremy P Kamil
doi: https://doi.org/10.1101/2021.02.12.21251658

7 US variants found; variants are related to each other; identified as Q677P

...Here, we describe evidence from two independent SARS-CoV-2 genomic surveillance programs in Louisiana and New Mexico that each detected the rise of S variants affecting position 677 in the later months of 2020. We further provide phylogenetic analyses that identify six independent Q677H sub-lineages and one Q677P sub-lineage that all appear to have emerged within the United States. These variants were not detected until mid-August 2020, but as of 03 Feb 2021 already account for over 2,327 of the 102,462 genomes deposited to GISAID from the USA...

https://www.medrxiv.org/content/10.1101/2021.02.12.21251658v1.full.pdf
 
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