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prepandemic vaccine strains

gsgs

Registered User
the current prepandemic vaccine recommendation of WHA involves
the hemagglutinin of strains:

Viet Nam/1194/2004
Viet Nam/1203/2004
Thailand/16/2004
Indonesia/5/2005
Indonesia/CDC357/2006
Indonesia/CDC625/2006
Turkey/15/2006
Whooping swan/Mongolia/244/2005
Bar headed Gs/Qinghai/1A/2005
Dk/Hunan/15/2004
Anhui/1/2005
Guangxi/1/2005
HK/213/2003
HK/156/97(H5N1)


however, the most central strains are:

21 Ck/HK/61.9/02
21 WildDk/Guangdong/314/04
22 Ck/HKi/86.3/02
22 Ck/Henan/210/04
22 Ck/Henan/12/04
23 Dk/Guangxi/50/01
23 swan/Guangxi/307/04
23 Ck/Hubei/489/04
23 Ck/Henan/01/04
23 Ck/Jilin/hh/02
23 swine/Guangxi/wz/04

while vaccine similar strains score:

27 HK/213/03
28 VNM/1203/04
29 VNM/1194/04
39 IDN/CDC357/06
30 Bar-headed Gs/Qinghai/59/05
31 Guangxi/1/05
32 Anhui/1/05
33 Ck/Dairi/BPPVI/05

after removing similar sequences we have scores:

21 001 WildDk/Guangdong/314/04
25 011 Dk/Guangdong/40/00
25 010 Ck/Jiangsu/cz1/02
26 003 cat/THA/KU-02/04
26 002 Dk/Hubei/wp/03

28 009 HK/213/03
34 068 HK/156/97
35 034 Ck/Dairi/BPPVI/05
35 014 Bar-headed Gs/Qinghai/59/05



so, I wonder why they didn't consider to include
the hemagglutitine of

21 Ck/HK/61.9/02
21 WildDk/Guangdong/314/04
22 Ck/Henan/12/04

in their recommendations or testings ?!
 
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