Shiloh
Editor, Senior Moderator
Source: http://www.upi.com/Science_News/201...t-beneficial-in-pneumonia/UPI-52061267038555/
Prednisolone not beneficial in pneumonia
Published: Feb. 24, 2010 at 2:09 PM
ALKMAAR, Netherlands, Feb. 24 (UPI) -- A Netherlands-led team of scientists says it has determined prednisolone is not beneficial in most cases of community-acquired pneumonia.
The researchers, led by Dr. Dominic Snijders of the Alkmaar Medical Center, said patients with mild to moderate pneumonia should not be routinely prescribed prednisolone, a corticosteroid, because it is associated with a recurrence of symptoms after its withdrawal.
The scientists said their findings came from the first randomized double-blind clinical trial to address the subject.
"Prednisolone therapy next to antibiotic therapy in patients hospitalized with (community-acquired pneumonia) should not be recommend due to lack of clinical benefit and a higher rate of late failures," Snijders said.
The researchers' findings appear in the early online edition of the American Journal of Respiratory and Critical Care Medicine.
Prednisolone not beneficial in pneumonia
Published: Feb. 24, 2010 at 2:09 PM
ALKMAAR, Netherlands, Feb. 24 (UPI) -- A Netherlands-led team of scientists says it has determined prednisolone is not beneficial in most cases of community-acquired pneumonia.
The researchers, led by Dr. Dominic Snijders of the Alkmaar Medical Center, said patients with mild to moderate pneumonia should not be routinely prescribed prednisolone, a corticosteroid, because it is associated with a recurrence of symptoms after its withdrawal.
The scientists said their findings came from the first randomized double-blind clinical trial to address the subject.
"Prednisolone therapy next to antibiotic therapy in patients hospitalized with (community-acquired pneumonia) should not be recommend due to lack of clinical benefit and a higher rate of late failures," Snijders said.
The researchers' findings appear in the early online edition of the American Journal of Respiratory and Critical Care Medicine.