tetano
Editor, Senior Moderator
PLoS One. 2013 Oct 4;8(10):e75226.
Potential Impact of Influenza A/H1N1 Pandemic and Hand-Gels on Acute Diarrhea Epidemic in France.
Cr?pey P, Pivette M, Desvarieux M.
Source
?cole des hautes ?tudes en sant? publique Rennes, Sorbonne Paris Cit?, Paris, France ; UMR EPV Emergence des Pathologies Virales -190, Aix-Marseille University, Marseille, France.
Abstract
BACKGROUND:
The 2009 A/H1N1 influenza pandemic has received a great deal of attention from public health authorities. Our study examines whether this pandemic and the resulting public health measures could have impacted acute diarrhea, a prevalent, highly transmissible and historically monitored disease.
METHODS:
Using augmentation procedures of national data for the previous five years (2004-2009), we estimated the expected timing and incidence of acute diarrhea in France in 2009-2010 and evaluated differences with the observed. We also reviewed national hand gels for the same period.
FINDINGS:
Number of episodes of acute diarrhea in France in 2009-2010 was significantly lower than expected until the third week of December (-24%, 95% CI [-36%; -9%]), then significantly higher (+40%, 95% CI [22%; 62%]), leading to a surplus of 574,440 episodes. The epidemic was delayed by 5 weeks with a peak 1.3 times higher than expected. Hand-gels sales inversely correlated with incidence of both influenza-like illness and acute diarrheal disease. Among individuals >65 yo, no excess cases of influenza and no excess rebound in acute diarrhea were observed, despite similar delay in the onset of the seasonal diarrheal epidemic.
INTERPRETATION:
Our results suggest that at least one endemic disease had an unexpected behavior in 2009-2010. Acute diarrhea seems to have been controlled during the beginning of the pandemic in all age groups, but later peaked higher than expected in the younger population. The all-age delay in seasonal onset seems partly attributable to hand-gels use, while the differential magnitude of the seasonal epidemic between young and old, concurrent for both influenza and acute diarrhea, is compatible with disease interaction.
PMID:
24124479
[PubMed - as supplied by publisher]
Free full text
http://www.ncbi.nlm.nih.gov/pubmed/24124479
Potential Impact of Influenza A/H1N1 Pandemic and Hand-Gels on Acute Diarrhea Epidemic in France.
Cr?pey P, Pivette M, Desvarieux M.
Source
?cole des hautes ?tudes en sant? publique Rennes, Sorbonne Paris Cit?, Paris, France ; UMR EPV Emergence des Pathologies Virales -190, Aix-Marseille University, Marseille, France.
Abstract
BACKGROUND:
The 2009 A/H1N1 influenza pandemic has received a great deal of attention from public health authorities. Our study examines whether this pandemic and the resulting public health measures could have impacted acute diarrhea, a prevalent, highly transmissible and historically monitored disease.
METHODS:
Using augmentation procedures of national data for the previous five years (2004-2009), we estimated the expected timing and incidence of acute diarrhea in France in 2009-2010 and evaluated differences with the observed. We also reviewed national hand gels for the same period.
FINDINGS:
Number of episodes of acute diarrhea in France in 2009-2010 was significantly lower than expected until the third week of December (-24%, 95% CI [-36%; -9%]), then significantly higher (+40%, 95% CI [22%; 62%]), leading to a surplus of 574,440 episodes. The epidemic was delayed by 5 weeks with a peak 1.3 times higher than expected. Hand-gels sales inversely correlated with incidence of both influenza-like illness and acute diarrheal disease. Among individuals >65 yo, no excess cases of influenza and no excess rebound in acute diarrhea were observed, despite similar delay in the onset of the seasonal diarrheal epidemic.
INTERPRETATION:
Our results suggest that at least one endemic disease had an unexpected behavior in 2009-2010. Acute diarrhea seems to have been controlled during the beginning of the pandemic in all age groups, but later peaked higher than expected in the younger population. The all-age delay in seasonal onset seems partly attributable to hand-gels use, while the differential magnitude of the seasonal epidemic between young and old, concurrent for both influenza and acute diarrhea, is compatible with disease interaction.
PMID:
24124479
[PubMed - as supplied by publisher]
Free full text
http://www.ncbi.nlm.nih.gov/pubmed/24124479