tetano
Editor, Senior Moderator
PLoS One
. 2020 Jul 10;15(7):e0235653.
doi: 10.1371/journal.pone.0235653. eCollection 2020.
Rate of Intensive Care Unit Admission and Outcomes Among Patients With Coronavirus: A Systematic Review and Meta-analysis
Semagn Mekonnen Abate[SUP] 1 [/SUP], Siraj Ahmed Ali[SUP] 1 [/SUP], Bahiru Mantfardo[SUP] 2 [/SUP], Bivash Basu[SUP] 3 [/SUP]
Affiliations
Abstract
Background: The rate of ICU admission among patients with coronavirus varied from 3% to 100% and the mortality was as high as 86% of admitted patients. The objective of the systematic review was to investigate the rate of ICU admission, mortality, morbidity, and complications among patients with coronavirus.
Methods: A comprehensive strategy was conducted in PubMed/Medline; Science direct and LILACS from December 2002 to May 2020 without language restriction. The Heterogeneity among the included studies was checked with forest plot, χ2 test, I2 test, and the p-values. All observational studies reporting rate of ICU admission, the prevalence of mortality and its determinants among ICU admitted patients with coronavirus were included and the rest were excluded.
Result: A total of 646 articles were identified from different databases and 50 articles were selected for evaluation. Thirty-seven Articles with 24983 participants were included. The rate of ICU admission was 32% (95% CI: 26 to 38, 37 studies and 32, 741 participants). The Meta-Analysis revealed that the pooled prevalence of mortality in patients with coronavirus disease in ICU was 39% (95% CI: 34 to 43, 37 studies and 24, 983 participants).
Conclusion: The Meta-Analysis revealed that approximately one-third of patients admitted to ICU with severe Coronavirus disease and more than thirty percent of patients admitted to ICU with a severe form of COVID-19 for better care died which warns the health care stakeholders to give attention to intensive care patients.
Registration: This Systematic review and Meta-Analysis was registered in Prospero international prospective register of systemic reviews (CRD42020177095) on April 9/2020.
. 2020 Jul 10;15(7):e0235653.
doi: 10.1371/journal.pone.0235653. eCollection 2020.
Rate of Intensive Care Unit Admission and Outcomes Among Patients With Coronavirus: A Systematic Review and Meta-analysis
Semagn Mekonnen Abate[SUP] 1 [/SUP], Siraj Ahmed Ali[SUP] 1 [/SUP], Bahiru Mantfardo[SUP] 2 [/SUP], Bivash Basu[SUP] 3 [/SUP]
Affiliations
- PMID: 32649661
- DOI: 10.1371/journal.pone.0235653
Abstract
Background: The rate of ICU admission among patients with coronavirus varied from 3% to 100% and the mortality was as high as 86% of admitted patients. The objective of the systematic review was to investigate the rate of ICU admission, mortality, morbidity, and complications among patients with coronavirus.
Methods: A comprehensive strategy was conducted in PubMed/Medline; Science direct and LILACS from December 2002 to May 2020 without language restriction. The Heterogeneity among the included studies was checked with forest plot, χ2 test, I2 test, and the p-values. All observational studies reporting rate of ICU admission, the prevalence of mortality and its determinants among ICU admitted patients with coronavirus were included and the rest were excluded.
Result: A total of 646 articles were identified from different databases and 50 articles were selected for evaluation. Thirty-seven Articles with 24983 participants were included. The rate of ICU admission was 32% (95% CI: 26 to 38, 37 studies and 32, 741 participants). The Meta-Analysis revealed that the pooled prevalence of mortality in patients with coronavirus disease in ICU was 39% (95% CI: 34 to 43, 37 studies and 24, 983 participants).
Conclusion: The Meta-Analysis revealed that approximately one-third of patients admitted to ICU with severe Coronavirus disease and more than thirty percent of patients admitted to ICU with a severe form of COVID-19 for better care died which warns the health care stakeholders to give attention to intensive care patients.
Registration: This Systematic review and Meta-Analysis was registered in Prospero international prospective register of systemic reviews (CRD42020177095) on April 9/2020.