tetano
Editor, Senior Moderator
PLoS One
. 2020 Oct 28;15(10):e0241170.
doi: 10.1371/journal.pone.0241170. eCollection 2020.
Estimation of the percentages of undiagnosed patients of the novel coronavirus (SARS-CoV-2) infection in Hokkaido, Japan by using birth-death process with recursive full tracing
Takuma Tanaka[SUP] 1 2 [/SUP], Takayuki Yamaguchi[SUP] 2 [/SUP], Yohei Sakamoto[SUP] 3 [/SUP]
Affiliations
Abstract
Estimating the percentages of undiagnosed and asymptomatic patients is essential for controlling the outbreak of SARS-CoV-2, and for assessing any strategy for controlling the disease. In this paper, we propose a novel analysis based on the birth-death process with recursive full tracing. We estimated the numbers of undiagnosed symptomatic patients and the lower bound of the number of total infected individuals per diagnosed patient before and after the declaration of the state of emergency in Hokkaido, Japan. The median of the estimated number of undiagnosed symptomatic patients per diagnosed patient decreased from 1.7 to 0.77 after the declaration, and the median of the estimated lower bound of the number of total infected individuals per diagnosed patient decreased from 4.2 to 2.4. We will discuss the limitations and possible expansions of the model.
. 2020 Oct 28;15(10):e0241170.
doi: 10.1371/journal.pone.0241170. eCollection 2020.
Estimation of the percentages of undiagnosed patients of the novel coronavirus (SARS-CoV-2) infection in Hokkaido, Japan by using birth-death process with recursive full tracing
Takuma Tanaka[SUP] 1 2 [/SUP], Takayuki Yamaguchi[SUP] 2 [/SUP], Yohei Sakamoto[SUP] 3 [/SUP]
Affiliations
- PMID: 33112895
- DOI: 10.1371/journal.pone.0241170
Abstract
Estimating the percentages of undiagnosed and asymptomatic patients is essential for controlling the outbreak of SARS-CoV-2, and for assessing any strategy for controlling the disease. In this paper, we propose a novel analysis based on the birth-death process with recursive full tracing. We estimated the numbers of undiagnosed symptomatic patients and the lower bound of the number of total infected individuals per diagnosed patient before and after the declaration of the state of emergency in Hokkaido, Japan. The median of the estimated number of undiagnosed symptomatic patients per diagnosed patient decreased from 1.7 to 0.77 after the declaration, and the median of the estimated lower bound of the number of total infected individuals per diagnosed patient decreased from 4.2 to 2.4. We will discuss the limitations and possible expansions of the model.