tetano
Editor, Senior Moderator
PLoS One
. 2023 Feb 6;18(2):e0281455.
doi: 10.1371/journal.pone.0281455. eCollection 2023.
Determinants of mortality among hospitalized patients with COVID-19 during first and second waves of the pandemic: A retrospective cohort study from an isolation center in Kano, Nigeria
Farouq Muhammad Dayyab[SUP] 1 2 [/SUP], Hussain Abdullahi Bashir[SUP] 2 3 [/SUP], Abdulwahab Kabir Sulaiman[SUP] 2 4 [/SUP], Garba Iliyasu[SUP] 5 [/SUP], Muhammad Hamza[SUP] 5 [/SUP], Ahmad Maifada Yakasai[SUP] 6 [/SUP], Ibrahim Nashabaru[SUP] 5 [/SUP], Hadiza Saidu[SUP] 4 7 [/SUP], Bashir Garba Ahmad[SUP] 3 [/SUP], Bashir Dabo[SUP] 8 [/SUP], Aminu Yusuf Abubakar[SUP] 2 [/SUP], Ibrahim Musa Idris[SUP] 2 [/SUP], Abdulrauf Sani Yahaya[SUP] 2 [/SUP], Mustapha Ado[SUP] 2 [/SUP], Ibrahim Sabo Abdurrahman[SUP] 2 [/SUP], Hafizu Musa Usman[SUP] 2 [/SUP], Mohammed Kabiru Bello[SUP] 2 [/SUP], Jaafar Suleiman Jaafar[SUP] 2 [/SUP], Anifowose Abdullahi[SUP] 2 [/SUP], Abubakar Muhammad Alhassan[SUP] 2 [/SUP], Abdulmalik Ahmad[SUP] 2 [/SUP], Alika Ehima Allen[SUP] 2 [/SUP], Medu Oghenekevwe Ezekiel[SUP] 2 [/SUP], Muhammad Abdullahi Umar[SUP] 2 [/SUP], Muhammad B Abdullahi[SUP] 2 [/SUP], Sahabi Kabir Sulaiman[SUP] 9 [/SUP], Tijjani Hussaini[SUP] 10 [/SUP], Amina Abdullahi Umar[SUP] 11 [/SUP], Aminu Ibrahim Tsanyawa[SUP] 12 [/SUP], Sabitu Y Shuaibu[SUP] 13 [/SUP], Nasir Alhassan Kabo[SUP] 14 [/SUP], Basheer Lawan Muhammad[SUP] 12 [/SUP], Mohammed Nura Yahaya[SUP] 10 [/SUP], Imam Wada Bello[SUP] 10 [/SUP], Ashiru Rajab[SUP] 12 [/SUP], Abdulhakim Muhammad Daiyab[SUP] 15 [/SUP], Aminu Faruk Kabara[SUP] 16 [/SUP], Muhammad Sule Garko[SUP] 17 [/SUP], Abdulrazaq Garba Habib[SUP] 5 [/SUP]
Affiliations
Abstract
Background: Coronavirus disease 2019 (COVID-19) has emerged as an important cause of morbidity and mortality worldwide. The aim of this study is to identify the clinical predictors of mortality among patients with COVID-19 pneumonia during first and second waves in a treatment center in northwestern Nigeria.
Methods: This was a retrospective cohort study of 195 patients hospitalized with COVID-19 between April 2020 to March 2021 at a designated COVID-19 isolation center in Kano State, Northwest Nigeria. Data were summarized using frequencies and percentages. Unadjusted odds ratios and 95% confidence intervals and p-values were obtained. To determine independent determinants of mortality, we performed a stepwise multivariate logistic regression model.
Results: Of 195 patients studied, 21(10.77%) patients died. Males comprised 158 (81.03%) of the study population. In the adjusted stepwise logistic regression analysis, age>64 years (OR = 9.476, 95% CI: 2.181-41.165), second wave of the pandemic (OR = 49.340, 95% CI:6.222-391.247), cardiac complications (OR = 24.984, 95% CI: 3.618-172.508), hypertension (OR = 5.831, 95% CI:1.413-24.065) and lowest systolic blood pressure while on admission greater than or equal to 90mmHg were independent predictors of mortality (OR = 0.111, 95%CI: 0.021-0.581).
Conclusion: Strategies targeted to prioritize needed care to patients with identified factors that predict mortality might improve patient outcome.
. 2023 Feb 6;18(2):e0281455.
doi: 10.1371/journal.pone.0281455. eCollection 2023.
Determinants of mortality among hospitalized patients with COVID-19 during first and second waves of the pandemic: A retrospective cohort study from an isolation center in Kano, Nigeria
Farouq Muhammad Dayyab[SUP] 1 2 [/SUP], Hussain Abdullahi Bashir[SUP] 2 3 [/SUP], Abdulwahab Kabir Sulaiman[SUP] 2 4 [/SUP], Garba Iliyasu[SUP] 5 [/SUP], Muhammad Hamza[SUP] 5 [/SUP], Ahmad Maifada Yakasai[SUP] 6 [/SUP], Ibrahim Nashabaru[SUP] 5 [/SUP], Hadiza Saidu[SUP] 4 7 [/SUP], Bashir Garba Ahmad[SUP] 3 [/SUP], Bashir Dabo[SUP] 8 [/SUP], Aminu Yusuf Abubakar[SUP] 2 [/SUP], Ibrahim Musa Idris[SUP] 2 [/SUP], Abdulrauf Sani Yahaya[SUP] 2 [/SUP], Mustapha Ado[SUP] 2 [/SUP], Ibrahim Sabo Abdurrahman[SUP] 2 [/SUP], Hafizu Musa Usman[SUP] 2 [/SUP], Mohammed Kabiru Bello[SUP] 2 [/SUP], Jaafar Suleiman Jaafar[SUP] 2 [/SUP], Anifowose Abdullahi[SUP] 2 [/SUP], Abubakar Muhammad Alhassan[SUP] 2 [/SUP], Abdulmalik Ahmad[SUP] 2 [/SUP], Alika Ehima Allen[SUP] 2 [/SUP], Medu Oghenekevwe Ezekiel[SUP] 2 [/SUP], Muhammad Abdullahi Umar[SUP] 2 [/SUP], Muhammad B Abdullahi[SUP] 2 [/SUP], Sahabi Kabir Sulaiman[SUP] 9 [/SUP], Tijjani Hussaini[SUP] 10 [/SUP], Amina Abdullahi Umar[SUP] 11 [/SUP], Aminu Ibrahim Tsanyawa[SUP] 12 [/SUP], Sabitu Y Shuaibu[SUP] 13 [/SUP], Nasir Alhassan Kabo[SUP] 14 [/SUP], Basheer Lawan Muhammad[SUP] 12 [/SUP], Mohammed Nura Yahaya[SUP] 10 [/SUP], Imam Wada Bello[SUP] 10 [/SUP], Ashiru Rajab[SUP] 12 [/SUP], Abdulhakim Muhammad Daiyab[SUP] 15 [/SUP], Aminu Faruk Kabara[SUP] 16 [/SUP], Muhammad Sule Garko[SUP] 17 [/SUP], Abdulrazaq Garba Habib[SUP] 5 [/SUP]
Affiliations
- PMID: 36745658
- DOI: 10.1371/journal.pone.0281455
Abstract
Background: Coronavirus disease 2019 (COVID-19) has emerged as an important cause of morbidity and mortality worldwide. The aim of this study is to identify the clinical predictors of mortality among patients with COVID-19 pneumonia during first and second waves in a treatment center in northwestern Nigeria.
Methods: This was a retrospective cohort study of 195 patients hospitalized with COVID-19 between April 2020 to March 2021 at a designated COVID-19 isolation center in Kano State, Northwest Nigeria. Data were summarized using frequencies and percentages. Unadjusted odds ratios and 95% confidence intervals and p-values were obtained. To determine independent determinants of mortality, we performed a stepwise multivariate logistic regression model.
Results: Of 195 patients studied, 21(10.77%) patients died. Males comprised 158 (81.03%) of the study population. In the adjusted stepwise logistic regression analysis, age>64 years (OR = 9.476, 95% CI: 2.181-41.165), second wave of the pandemic (OR = 49.340, 95% CI:6.222-391.247), cardiac complications (OR = 24.984, 95% CI: 3.618-172.508), hypertension (OR = 5.831, 95% CI:1.413-24.065) and lowest systolic blood pressure while on admission greater than or equal to 90mmHg were independent predictors of mortality (OR = 0.111, 95%CI: 0.021-0.581).
Conclusion: Strategies targeted to prioritize needed care to patients with identified factors that predict mortality might improve patient outcome.