tetano
Editor, Senior Moderator
PLoS One
. 2022 Jun 16;17(6):e0267835.
doi: 10.1371/journal.pone.0267835. eCollection 2022.
Acute respiratory distress syndrome among patients with severe COVID-19 admitted to treatment center of Wollega University Referral Hospital, Western Ethiopia
Tadesse Tolossa[SUP] 1 [/SUP], Emiru Merdassa Atomssa[SUP] 1 [/SUP], Getahun Fetensa[SUP] 2 3 [/SUP], Lami Bayisa[SUP] 2 [/SUP], Diriba Ayala[SUP] 4 [/SUP], Ebisa Turi[SUP] 1 [/SUP], Bizuneh Wakuma[SUP] 2 [/SUP], Diriba Mulisa[SUP] 2 [/SUP], Dejene Seyoum[SUP] 1 [/SUP], Ayantu Getahun[SUP] 1 [/SUP], Tesfaye Shibiru[SUP] 5 [/SUP], Ginenus Fekadu[SUP] 6 7 [/SUP], Markos Desalegn[SUP] 1 [/SUP], Haile Bikila[SUP] 1 [/SUP]
Affiliations
Abstract
Background: Acute respiratory distress syndrome is a life-threatening condition that has a significant effect on the occurrence of morbidity and mortality among patients with severe Coronavirus disease 2019 (COVID-19). To the best of researchers' knowledge, there is no Study on ARDS of COVID-19 in Ethiopia. Therefore, this study aimed to identify the prevalence of ARDS and associated factors among severe COVID-19 patients at Wollega University Referral Hospital.
Methods: An institution-based retrospective cross-sectional study was conducted from September 20, 2020, to June 10, 2021. Real-Time Reverse transcription-polymerase Chain Reaction (rRT-PCR) test was used to test Patients for COVID-19. Epi-data version 3.2 was used for data entry, and the final data analysis was through STATA version 14. After checking the assumption P-value<0.25 in the bivariable analysis was used to select a candidate variable for multi-variable analysis, and a p-value of <0.05 was used to declare statistical significance.
Results: In this study, the prevalence of ARDS was 32%. Almost all the patients had the clinical feature of cough (93.7%), followed by shortness of breath (79.9%), fever (77.7%), and headache (67%). Age older than 65 years (AOR = 3.35, 95%CI = 1.31, 8.55), male gender (AOR = 5.63, 95%CI = 2.15, 14.77), and low oxygen saturation level (AOR = 4.60, 95%CI = 1.15, 18.35) were the independent predictors of ARDS among severe COVID-19 patients.
Conclusion: The prevalence of ARDS among patients with severe COVID-19 was high in the study area. Therefore, elders and patients with critical conditions (low oxygen saturation) better to get special attention during COVID-19 case management to enhance good care and monitoring of the patients.
. 2022 Jun 16;17(6):e0267835.
doi: 10.1371/journal.pone.0267835. eCollection 2022.
Acute respiratory distress syndrome among patients with severe COVID-19 admitted to treatment center of Wollega University Referral Hospital, Western Ethiopia
Tadesse Tolossa[SUP] 1 [/SUP], Emiru Merdassa Atomssa[SUP] 1 [/SUP], Getahun Fetensa[SUP] 2 3 [/SUP], Lami Bayisa[SUP] 2 [/SUP], Diriba Ayala[SUP] 4 [/SUP], Ebisa Turi[SUP] 1 [/SUP], Bizuneh Wakuma[SUP] 2 [/SUP], Diriba Mulisa[SUP] 2 [/SUP], Dejene Seyoum[SUP] 1 [/SUP], Ayantu Getahun[SUP] 1 [/SUP], Tesfaye Shibiru[SUP] 5 [/SUP], Ginenus Fekadu[SUP] 6 7 [/SUP], Markos Desalegn[SUP] 1 [/SUP], Haile Bikila[SUP] 1 [/SUP]
Affiliations
- PMID: 35709142
- DOI: 10.1371/journal.pone.0267835
Abstract
Background: Acute respiratory distress syndrome is a life-threatening condition that has a significant effect on the occurrence of morbidity and mortality among patients with severe Coronavirus disease 2019 (COVID-19). To the best of researchers' knowledge, there is no Study on ARDS of COVID-19 in Ethiopia. Therefore, this study aimed to identify the prevalence of ARDS and associated factors among severe COVID-19 patients at Wollega University Referral Hospital.
Methods: An institution-based retrospective cross-sectional study was conducted from September 20, 2020, to June 10, 2021. Real-Time Reverse transcription-polymerase Chain Reaction (rRT-PCR) test was used to test Patients for COVID-19. Epi-data version 3.2 was used for data entry, and the final data analysis was through STATA version 14. After checking the assumption P-value<0.25 in the bivariable analysis was used to select a candidate variable for multi-variable analysis, and a p-value of <0.05 was used to declare statistical significance.
Results: In this study, the prevalence of ARDS was 32%. Almost all the patients had the clinical feature of cough (93.7%), followed by shortness of breath (79.9%), fever (77.7%), and headache (67%). Age older than 65 years (AOR = 3.35, 95%CI = 1.31, 8.55), male gender (AOR = 5.63, 95%CI = 2.15, 14.77), and low oxygen saturation level (AOR = 4.60, 95%CI = 1.15, 18.35) were the independent predictors of ARDS among severe COVID-19 patients.
Conclusion: The prevalence of ARDS among patients with severe COVID-19 was high in the study area. Therefore, elders and patients with critical conditions (low oxygen saturation) better to get special attention during COVID-19 case management to enhance good care and monitoring of the patients.