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PLoS Negl Top. Dis. A 6-Year-Old Child with Severe Ebola Virus Disease: Laboratory-Guided Clinical Care in an Ebola Treatment Center in Guinea

tetano

Editor, Senior Moderator
Citation: Palich R, Gala J-L, Petitjean F, Shepherd S, Peyrouset O, Abdoul BM, et al. (2016) A 6-Year-Old Child with Severe Ebola Virus Disease: Laboratory-Guided Clinical Care in an Ebola Treatment Center in Guinea. PLoS Negl Trop Dis 10(3): e0004393. doi:10.1371/journal.pntd.0004393
[h=2]Context[/h] An unprecedented epidemic of Ebola virus disease has ravaged West Africa since December, 2013 [1].
The French nongovernmental organization Alliance for International Medical Action opened the N?z?r?kor? Ebola treatment center (ETC) on December 2nd, 2014. This center includes a laboratory managed by the Belgian organization B-Fast/B-Life. Between December 2nd, 2014, and February 7th, 2015, 130 patients were admitted, of whom 76 were confirmed to have Ebola virus disease (EVD), which was fatal in 60.8%.
Since December 26th, 2014, the N?z?r?kor? ETC has been a clinical trial site, participating in a multicenter study to evaluate the ability of a 10-day course of the oral antiviral agent favipiravir to reduce mortality in Ebola-infected adults and children aged over 1 year [2].
[h=2]Case Presentation[/h] Our 6-year-old patient was likely infected by his mother, who was admitted to the center with EVD on December 19th, 2014. She died 2 days later. The patient?s father was admitted to the center on December 31st and tested positive. He cleared Ebola virus (EBOV) as of January 5th but remained in the ward as long as his child was hospitalized. The patient?s aunt has given consent to the publication of this case report.

full article

http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0004393
 
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