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Pigeons reservoir for H5N1?

Ganseerpel

Advisory Board, Senior Moderator
(Obliter dictu)
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Several studies have demonstrated that pigeons are particular resistant to AI Viruses. (2) (3), but only few were focussed on H5N1 Types. <o:p></o:p>
Most experiments show a minor infection rate and mortality, low percentage of antibody responders and virusshedding. <o:p></o:p>
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A recent work (1) using several currently circulating strains (a) in China confirmed a higher resistance (< 37,5 % DR, most strains no lethality) to challenge in comparison to chickens and quails, but showed, that all tested pigeons had positive tissue samples from glandular stomach. Identification of virus in tissues is not common in pigeons and the new finding indicates that pigeons might be carriers of avian influenza virus.<o:p></o:p>
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(1) Meilin Jin, State Key Laboratory of Agriculture Microbiology Laboratory of Animal Virology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, People's Republic of China; email: jml8328@126.com http://www.cdc.gov/eid/content/13/5/772.htm#cit<o:p></o:p>
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(2) Panigrahy B, Senne DA, Pedersen JC, Shafer AL, Pearson JE. Susceptibility of pigeons to avian influenza. Avian Dis. 1996 Jul-Sep;40(3):600-4.<o:p></o:p>
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(3) Kaleta EF, Hönicke A: Review of the literature on avian influenza A viruses in pigeons and experimental studies on the susceptibility of domestic pigeons to influenza A viruses of the haemagglutinin subtype H7.<o:p></o:p>
Dtsch Tierarztl Wochenschr. 2004 Dec;111(12):467-72<o:p></o:p>
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(a) strains used in the experiments:<o:p></o:p>
A/widgeon/Hubei/EWHC/2004 (EWHC), <o:p></o:p>
A/chicken/Hubei/327/2004 (CKDW), <o:p></o:p>
A/chicken/Hubei/JZJ/2004 (CKJZ),
A/chicken/Hubei/TMJ/2004 (CKTM),
A/chicken/Hubei/XFJ/2004 (CKXF), <o:p></o:p>
A/goose/Hubei/ZFE/2004 (GOZF), <o:p></o:p>
A/duck/Hubei/XFY/2004 (DKXF).<o:p></o:p>
 
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