tetano
Editor, Senior Moderator
Epidemiol Mikrobiol Imunol. 2013 Feb;62(1):4-8.
[Phylogenetic Analysis and Genotyping of A/H3N2 Influenza Viruses Isolated from Patients Hospitalised with Influenza-Like Illness Symptoms in the Na Bulovce Hospital in the Season 2011/2012].
[Article in Czech]
Alexander N, Helena J, Martina H, Olga D, Krist?na H, Milan T, Vilma M, Ludmila N, Jan K.
Abstract
Influenza A virus is an important cause of acute respiratory infections (ARI). Clinical manifestations of ARI vary from mild or moderate to life-threatening conditions requiring intensive care. Given the segmented genome, a large natural reservoir of other influenza virus subtypes, and antibody selection pressure in the population, the virus is variable and genetically unstable. The phylogenetic analysis and genotyping of A/H3N2 influenza viruses isolated from patients hospitalised with influenza-like illness symptoms in the Na Bulovce Hospital in the season 2011/2012 support the assumption that the pathogenicity is a polygenic trait modifiable by the host health status and seems not to be unambiguously associated with any specific mutations. Keywords: influenza A virus, phylogenetic analysis - genotyping - hospitalization - clinical symptoms.
PMID:
23768089
[PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/23768089
[Phylogenetic Analysis and Genotyping of A/H3N2 Influenza Viruses Isolated from Patients Hospitalised with Influenza-Like Illness Symptoms in the Na Bulovce Hospital in the Season 2011/2012].
[Article in Czech]
Alexander N, Helena J, Martina H, Olga D, Krist?na H, Milan T, Vilma M, Ludmila N, Jan K.
Abstract
Influenza A virus is an important cause of acute respiratory infections (ARI). Clinical manifestations of ARI vary from mild or moderate to life-threatening conditions requiring intensive care. Given the segmented genome, a large natural reservoir of other influenza virus subtypes, and antibody selection pressure in the population, the virus is variable and genetically unstable. The phylogenetic analysis and genotyping of A/H3N2 influenza viruses isolated from patients hospitalised with influenza-like illness symptoms in the Na Bulovce Hospital in the season 2011/2012 support the assumption that the pathogenicity is a polygenic trait modifiable by the host health status and seems not to be unambiguously associated with any specific mutations. Keywords: influenza A virus, phylogenetic analysis - genotyping - hospitalization - clinical symptoms.
PMID:
23768089
[PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/23768089