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Phased introduction of a universal childhood influenza vaccination programme in England: Population-level factors predicting variation in national upt

tetano

Editor, Senior Moderator
Vaccine. 2015 Mar 30. pii: S0264-410X(15)00357-6. doi: 10.1016/j.vaccine.2015.03.049. [Epub ahead of print]
[h=1]Phased introduction of a universal childhood influenza vaccination programme in England: Population-level factors predicting variation in national uptake during the first year, 2013-14.[/h] Green HK[SUP]1[/SUP], Andrews N[SUP]2[/SUP], Letley L[SUP]2[/SUP], Sunderland A[SUP]2[/SUP], White J[SUP]2[/SUP], Pebody R[SUP]2[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] [h=4]INTRODUCTION:[/h] Through a phased rollout, the UK is implementing annual influenza vaccination for all healthy children aged 2-16 years old. In the first year of the programme in England in 2013/14, all 2-3 year olds were offered influenza vaccine through primary care and a primary school age programme was piloted mainly through schools in geographically distinct areas. Equitable delivery is a key aim of the programme; it is unclear if concerns by some religious groups over influenza vaccine content have impacted on uptake.
[h=4]METHODS:[/h] At the end of the 2013/14 season, variations in uptake for 2-3 year olds and 4-11 year olds were assessed and stratified by population-level predictors: deprivation, ethnicity, religious beliefs and rurality. GP practice or school level uptake was linearly regressed against these variables to determine potential predictors and changes in uptake, adjusting for significant factors.
[h=4]RESULTS:[/h] Uptake varied considerably by geographic locality for both age groups. Lower uptake was seen in increasingly deprived areas, with an adjusted uptake in the most deprived quintile 12% and 8% lower than the least deprived areas by age-group respectively. By ethnicity, the highest non-white population quartile had an adjusted uptake 9% and 14% lower than the lowest non-white quartile by age-group respectively. Uptake also varied according to religious belief, with adjusted uptake in the highest Muslim population tertile 8% lower than the lowest Muslim population tertile in 4-11 year olds.
[h=4]CONCLUSION:[/h] In the first season of the childhood influenza vaccination programme, uptake was not uniform across the country, with deprivation and ethnicity both predictors of low uptake in pre-school and primary school age children, and religious beliefs also an important factor particularly in the latter group. With the continued rollout of the programme, these population-level factors should be addressed to achieve sustained successful uptake, along with assessment of contribution of individual and household-level factors.
Copyright ? 2015. Published by Elsevier Ltd.


[h=4]KEYWORDS:[/h] Children; Epidemiology; Influenza; Vaccination

PMID: 25835576 [PubMed - as supplied by publisher]
 
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