tetano
Editor, Senior Moderator
Cell. 2014 Apr 10;157(2):294-9. doi: 10.1016/j.cell.2014.03.023.
Peering into the crystal ball: influenza pandemics and vaccine efficacy.
Miller MS1, Palese P2.
Author information
Abstract
The looming threat of a new influenza virus pandemic has fueled ambitious efforts to devise more predictive parameters for assessing the risks associated with emergent virus strains. At the same time, a comprehensive understanding of critical factors that can accurately predict the outcome of vaccination is sorely needed in order to improve the effectiveness of influenza virus vaccines. Will new studies aimed at identifying adaptations required for virus transmissibility and systems-level analyses of influenza virus vaccine responses provide an improved framework for predictive models of viral adaptation and vaccine efficacy?
Copyright ? 2014 Elsevier Inc. All rights reserved.
PMID:
24725400
[PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/24725400
Peering into the crystal ball: influenza pandemics and vaccine efficacy.
Miller MS1, Palese P2.
Author information
Abstract
The looming threat of a new influenza virus pandemic has fueled ambitious efforts to devise more predictive parameters for assessing the risks associated with emergent virus strains. At the same time, a comprehensive understanding of critical factors that can accurately predict the outcome of vaccination is sorely needed in order to improve the effectiveness of influenza virus vaccines. Will new studies aimed at identifying adaptations required for virus transmissibility and systems-level analyses of influenza virus vaccine responses provide an improved framework for predictive models of viral adaptation and vaccine efficacy?
Copyright ? 2014 Elsevier Inc. All rights reserved.
PMID:
24725400
[PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/24725400