tetano
Editor, Senior Moderator
Pediatr Radiol
. 2021 Apr 1.
doi: 10.1007/s00247-021-05055-2. Online ahead of print.
Pulmonary imaging in coronavirus disease 2019 (COVID-19): a series of 140 Latin American children
Carlos F Ugas-Charcape[SUP] 1 [/SUP], Mar?a Elena Ucar[SUP] 2 [/SUP], Judith Almanza-Aranda[SUP] 3 [/SUP], Emiliana Rizo-Patr?n[SUP] 4 [/SUP], Claudia Lazarte-Rantes[SUP] 5 [/SUP], Pablo Caro-Dom?nguez[SUP] 6 [/SUP], Lina Cadavid[SUP] 7 [/SUP], Lizbet P?rez-Marrero[SUP] 8 [/SUP], Tatiana Fazecas[SUP] 9 [/SUP], Luc?a Gomez[SUP] 10 [/SUP], Mariana S?nchez Curiel[SUP] 11 [/SUP], Walter Pacheco[SUP] 12 [/SUP], Ana Rizzi[SUP] 13 [/SUP], Andr?s Garc?a-Bayce[SUP] 14 [/SUP], Efigenia Bendeck[SUP] 15 [/SUP], Mario Monta?o[SUP] 16 [/SUP], Pedro Daltro[SUP] 17 [/SUP], Jos? D Arce-V[SUP] 18 [/SUP]
Affiliations
Abstract
Background: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which resulted in the worldwide coronavirus disease 2019 (COVID-19) pandemic of 2020, has particularly affected Latin America.
Objective: The purpose of the study was to analyze the imaging findings of pulmonary COVID-19 in a large pediatric series.
Materials and methods: Children with SARS-CoV-2 infection confirmed by either quantitative reverse transcription-polymerase chain reaction from nasopharyngeal swabs or presence of circulating immunoglobulin M (IgM) antibodies and who underwent chest radiograph or CT or both were included in this retrospective multicenter study. Three pediatric radiologists independently reviewed radiographs and CTs to identify the presence, localization, distribution and extension of pulmonary lesions.
Results: We included 140 children (71 female; median age 6.3 years, interquartile range 1.6-12.1 years) in the study. Peribronchial thickening (93%), ground-glass opacities (79%) and vascular engorgement (63%) were the most frequent findings on 131 radiographs. Ground-glass opacities (91%), vascular engorgement (84%) and peribronchial thickening (72%) were the most frequent findings on 32 CTs. Peribronchial thickening (100%), ground-glass opacities (83%) and pulmonary vascular engorgement (79%) were common radiograph findings in asymptomatic children (n=25). Ground-glass opacity and consolidation were significantly higher in children who needed intensive care admission or died (92% and 48%), in contrast with children with a favorable outcome (71% and 24%, respectively; P<0.05).
Conclusion: Asymptomatic children and those with mild symptoms of COVID-19 showed mainly peribronchial thickening, ground-glass opacities and pulmonary vascular engorgement on radiographs. Ground-glass opacity and consolidation were more common in children who required intensive care admission or died.
Keywords: Chest; Children; Computed tomography; Coronavirus disease 2019; Lungs; Pulmonary; Radiography; Severe acute respiratory syndrome coronavirus 2.
. 2021 Apr 1.
doi: 10.1007/s00247-021-05055-2. Online ahead of print.
Pulmonary imaging in coronavirus disease 2019 (COVID-19): a series of 140 Latin American children
Carlos F Ugas-Charcape[SUP] 1 [/SUP], Mar?a Elena Ucar[SUP] 2 [/SUP], Judith Almanza-Aranda[SUP] 3 [/SUP], Emiliana Rizo-Patr?n[SUP] 4 [/SUP], Claudia Lazarte-Rantes[SUP] 5 [/SUP], Pablo Caro-Dom?nguez[SUP] 6 [/SUP], Lina Cadavid[SUP] 7 [/SUP], Lizbet P?rez-Marrero[SUP] 8 [/SUP], Tatiana Fazecas[SUP] 9 [/SUP], Luc?a Gomez[SUP] 10 [/SUP], Mariana S?nchez Curiel[SUP] 11 [/SUP], Walter Pacheco[SUP] 12 [/SUP], Ana Rizzi[SUP] 13 [/SUP], Andr?s Garc?a-Bayce[SUP] 14 [/SUP], Efigenia Bendeck[SUP] 15 [/SUP], Mario Monta?o[SUP] 16 [/SUP], Pedro Daltro[SUP] 17 [/SUP], Jos? D Arce-V[SUP] 18 [/SUP]
Affiliations
- PMID: 33791841
- DOI: 10.1007/s00247-021-05055-2
Abstract
Background: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which resulted in the worldwide coronavirus disease 2019 (COVID-19) pandemic of 2020, has particularly affected Latin America.
Objective: The purpose of the study was to analyze the imaging findings of pulmonary COVID-19 in a large pediatric series.
Materials and methods: Children with SARS-CoV-2 infection confirmed by either quantitative reverse transcription-polymerase chain reaction from nasopharyngeal swabs or presence of circulating immunoglobulin M (IgM) antibodies and who underwent chest radiograph or CT or both were included in this retrospective multicenter study. Three pediatric radiologists independently reviewed radiographs and CTs to identify the presence, localization, distribution and extension of pulmonary lesions.
Results: We included 140 children (71 female; median age 6.3 years, interquartile range 1.6-12.1 years) in the study. Peribronchial thickening (93%), ground-glass opacities (79%) and vascular engorgement (63%) were the most frequent findings on 131 radiographs. Ground-glass opacities (91%), vascular engorgement (84%) and peribronchial thickening (72%) were the most frequent findings on 32 CTs. Peribronchial thickening (100%), ground-glass opacities (83%) and pulmonary vascular engorgement (79%) were common radiograph findings in asymptomatic children (n=25). Ground-glass opacity and consolidation were significantly higher in children who needed intensive care admission or died (92% and 48%), in contrast with children with a favorable outcome (71% and 24%, respectively; P<0.05).
Conclusion: Asymptomatic children and those with mild symptoms of COVID-19 showed mainly peribronchial thickening, ground-glass opacities and pulmonary vascular engorgement on radiographs. Ground-glass opacity and consolidation were more common in children who required intensive care admission or died.
Keywords: Chest; Children; Computed tomography; Coronavirus disease 2019; Lungs; Pulmonary; Radiography; Severe acute respiratory syndrome coronavirus 2.